Acanthosis nigricans has been associated with:
June 02, 2015
- Insulin resistance. Most people who have acanthosis nigricans have also become resistant to insulin. Insulin is a hormone secreted by the pancreas that allows your body to process sugar. Insulin resistance is what eventually causes type 2 diabetes.
- Hormonal disorders. Acanthosis nigricans often occurs in people who have disorders such as ovarian cysts, underactive thyroids or problems with the adrenal glands.
- Certain drugs and supplements. High-dose niacin, birth control pills, prednisone and other corticosteroids may cause acanthosis nigricans.
- Cancer. Acanthosis nigricans also sometimes occurs with lymphoma or when a cancerous tumor begins growing in an internal organ, such as the stomach, colon or liver.
- AskMayoExpert. Polycystic ovary syndrome. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2014.
- Habif TP. Cutaneous manifestations of internal disease. In: Clinical Dermatology: A Color Guide to Diagnosis and Therapy. 5th ed. Edinburgh, U.K.; New York, N.Y.: Mosby Elsevier; 2010. http://www.clinicalkey.com. Accessed March 25, 2015.
- Niacin and niacinamide (vitamin B3). Natural Medicines Comprehensive Database. http://naturaldatabase.therapeuticresearch.com. Accessed March 27, 2015.
- Gibson LE. Acanthosis nigricans. Mayo Clinic Proceedings. 2004;79:1571.
- Goldsmith LA, et al., eds. Diabetes Mellitus and other endocrine diseases. In: Fitzpatrick's Dermatology in General Medicine. 8th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com. Accessed March 25, 2015.
- Goldsmith LA, et al., eds. Cutaneous manifestations of internal malignant disease. In: Fitzpatrick's Dermatology in General Medicine. 8th ed. New York, N.Y.: The McGraw-Hill Companies; 2012. http://www.accessmedicine.com. Accessed March 25, 2015.
- Braunstein I. Acanthosis nigricans. http://www.uptodate.com/home. Accessed March 25, 2015.