Eligibility

People with type 1 diabetes often may be candidates for a pancreas transplant. Some people with type 2 diabetes and post-total pancreatectomy diabetes may be eligible for a pancreas transplant.

Doctors recommend pancreas transplants for people with diabetes to:

  • Reduce or eliminate the risk of severe low blood sugar reactions
  • Eliminate the need for insulin injections
  • Potentially prevent or improve diabetes complications
  • Improve quality of life

Your transplant team will evaluate you to determine whether a pancreas transplant may be safe and beneficial for you. Your comprehensive evaluation includes blood tests, imaging studies and other tests. Doctors will check you for other serious conditions, including heart and blood vessel (cardiovascular) disease, cancer, foot or leg ulcers, and significant insulin resistance.

June 24, 2016
References
  1. Barbara Woodward Lips Patient Education Center. Pancreas transplant. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2013.
  2. U.S. News & World Report. U.S. News Best Hospitals 2015-16. http://health.usnews.com/best-hospitals/rankings. Accessed Feb. 22, 2016.
  3. Robertson RP. Pancreas and islet cell transplantation in diabetes mellitus. http://www.uptodate.com/home. Accessed April 7, 2016.
  4. Klein C, et al. Benefits and complications associated with kidney-pancreas transplantation in diabetes mellitus. http://www.uptodate.com/home. Accessed April 7, 2016.
  5. Barbara Woodward Lips Patient Education Center. Planning for your transplant: A financial guide. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2014.
  6. Riggin ER. Allscripts EPSi. Mayo Clinic, Rochester, Minn. April 6, 2016.
  7. Eggebraaten KR (expert opinion). Mayo Clinic, Rochester, Minn. April 18, 2016.
  8. Heilman RL, et al. Immunosuppression in simultaneous pancreas-kidney transplantation. Drugs. 2010;70:793.
  9. Lu B, et al. Beta-cell targeted gene delivery for enhanced beta-cell proliferation. Human Gene Therapy. 2015;26:A63.
  10. Stulak JM, et al. Combined heart and abdominal organ transplantation: Excellent outcomes gained from a unique experience. Journal of Heart and Lung Transplantation. 2014;33(suppl):S278.
  11. Kudva YC (expert opinion). Mayo Clinic, Rochester, Minn. March 14, 2016.
  12. Pancreas Transplant. National Kidney Foundation. https://www.kidney.org/atoz/content/pancreastx. Accessed April 12, 2016.