Clostridium difficile (C. difficile) is a bacterium commonly found in your intestines. Sometimes antibiotics used to treat an infection kill good bacteria, allowing C. difficile to grow out of control. C. difficile infection can cause symptoms ranging from diarrhea to life-threatening inflammation of the colon. C. difficile infection is a common and potentially serious complication from a stay in a hospital or long-term care facility.
Mayo Clinic in Rochester, Minn., ranks No. 1 for digestive disorders in the U.S. News & World Report Best Hospitals rankings. Mayo Clinic in Scottsdale, Ariz., and Mayo Clinic in Jacksonville, Fla., are ranked high performing for digestive disorders by U.S. News & World Report.