Alfredo Quinones-Hinojosa, M.D.

  1. Neurosurgeon
  2. Chair, Neurosurgery, Florida
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My name is Alfredo Quinones-Hinojosa, I'm the Mayo Professor of Neurosurgery at the Mayo Clinic in Florida. I have been working for over 18 years in the field of brain surgery. I get to see some of the most complex brain tumors you can possibly imagine, and these are tumors that are considered many times to be inoperable. The way that I think about a diagnosis and a treatment plan is, I look at the patient, I look at what the patient has. I don't just concentrate on the films, I don't just concentrate on the disease, I concentrate on the patient, and I try to tailor my treatment to what the patient needs. The most important thing for me about my interaction with the patients, is the fact that I consider to be a privilege. The fact that they allow me to take care of them every single day, and to me that is a gift that I take very seriously. It allows me to give them my best, not only as a surgeon, but also as a human being, and more importantly, as a physician that cares for them.

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Alfredo Quinones-Hinojosa, M.D., is a consultant and serves as chair of the Department of Neurologic Surgery at Mayo Clinic's campus in Florida, and he is recognized with the distinction of a named professorship, the William J. and Charles H. Mayo Professorship. His clinical focus includes:

  • Surgical treatment of primary and metastatic brain tumors with emphasis in motor and speech mapping during surgery
  • Pituitary tumors and skull base tumors using transsphenoidal endonasal and minimally invasive approaches
  • Providing personalized medicine to improve patient outcomes

In addition to his clinical activities, Dr. Quinones-Hinojosa leads NIH-funded research to find a cure for brain cancer. His cutting-edge research focuses on brain tumors and cell migration, health care disparities and clinical outcomes for neurosurgical patients in which the operating room is used as an extension for his research scenario. He has authored numerous high-impact scientific journal articles, chapters, abstracts and books.

Dr. Quinones-Hinojosa also continues to provide mentorship to residents, graduate students and fellows.

  1. Brain metastasis
  2. Brain tumor
  3. Metastatic brain tumor
  4. Pituitary tumor
  1. Brain tumor surgery
  2. Pituitary tumor surgery
  3. Radiation therapy

Clinical

  • Practice focuses on the surgical treatment of primary and metastatic brain tumors, with an emphasis on motor and speech mapping during surgery and in the treatment of patients with pituitary tumors and minimal invasive approaches of skull base tumors

Research

  • Research focuses on brain tumors and stem cell migration, healthcare disparities for minorities and clinical outcomes for neurosurgical patients
  • Major research accomplishments include:
    • Elucidating mechanisms by which brain tumors migrate
    • Integrating the use of mesenchymal stem cells into local treatment of solid tumors
    • Concomitant use of nanotechnology and focal beam radiotherapy in the systemic treatment of solid tumors
    • Development of new imaging software to help identify areas within solid tumors with the greatest malignant potential
    • Development of innovative, minimally invasive approaches to brain tumor resection
  • Elucidating mechanisms by which brain tumors migrate
  • Integrating the use of mesenchymal stem cells into local treatment of solid tumors
  • Concomitant use of nanotechnology and focal beam radiotherapy in the systemic treatment of solid tumors
  • Development of new imaging software to help identify areas within solid tumors with the greatest malignant potential
  • Development of innovative, minimally invasive approaches to brain tumor resection
  1. 2005
    Residency - NeurosurgeryUniversity of California San Francisco
  2. 2004
    Postdoctoral Fellowship - Developmental and Stem Cell BiologyUniversity of California San Francisco
  3. 2000
    Internship - General SurgeryUniversity of California San Francisco
  4. 1999
    Research Fellowship - Bristol-Myers Academic Medicine Fellowship; Studied the use of the intraoperative MRI in brain tumor biopsies. Advisor: Dr. Peter McL. Black.Harvard Medical School
  5. 1999
    Research Fellowship - Howard Hughes Fellowship; Examined the effects of coenzyme Q10 with nicotinamide; creatine and cyclocreatine (i) in the in vitro rabbit retina preparation, and (ii) in a n in vivo model of focal cerebral ischemia in the rat. Advisors: Dr. Chris Ogilvy and Dr. Ken Maynard.Massachusetts General Hospital and Harvard Medical School
  6. 1999
    MD - Thesis: Ischemia studies in the rabbit retina in vitro: neuroprotection by metabolic inhibitionHarvard Medical School
  7. 1996
    Research Fellowship - Neurobiology Training Grant Fellowship: Cloned a piece of the ecdysone-steroid receptor gene from the American lobster, Homarus americanus which plays a role in the aggressive behavior. Advisor: Dr. Edward A. Kravitz.Harvard Medical School
  8. 1994
    Research Fellowship - Ford Baccalaureate Fellowship; Investigated the role of Long Term Potentiation in the Nucleus Accumbens of the Rodent. Advisor: Dr. Joe L. MartinezUniversity of California Berkeley
  9. 1994
    BA - Psychology, Thesis: Long-term pontentation at the lateral perforant path-nucleus accumbens synapse in the rat in vivoUniversity of California Berkeley
  10. 1993
    Research Scholar - Medical School Summer Research Program; investigated the role of drugs and lethal injuries in New York City. Advisors: Dr. Kenneth Tardiff and Dr. Peter MarzukCornell University
  11. 1991
    Undergraduate Studies - Transferred core curriculum to the University of CaliforniaSan Joaquin Delta College
  12. 1986
    BA - Social Sciences and Humanities, Multidisciplinary teaching licenseEscuela Normal Urbana Federal Fronteriza
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Certifications

  1. 2010
    Neurological SurgeryAmerican Board of Neurological Surgery

Awards and honors

  1. 2015
    Commencement speakerCristo Rey Jesuit High School
  2. 2015
    Commencement speakerNotre Dame University
  3. 2015
    Doctor of Humane Letters: Honoris CausaDominican University
  4. 2015
    Doctor of Science: Honoris CausaUniversity of Notre Dame
  5. 2015
    VII Premio Iberoamericano Cortes de Cádiz de CirugíaPremios Cortes de Cádiz
  6. 2015
    Mexico’s most brilliant minds in the worldForbes
  7. 2015
    Galardón a la “Trayectoria Inspiradora”Instituto Mexicano de Mejores Prácticas Corporativas
  8. 2014
    First Place in Oncology CategoryBritish Medical Association
  9. 2014
    Neurosurgeon of the YearVoices Against Brain Cancer
  10. 2014
    Distinguished GuestCentro Medico ABC
  11. 2014
    Nifty Fifty ScientistUSA Science & Engineering Festival
  12. 2014
    Maryland Sister State AwardMaryland Sister State Program
  13. 2014
    Gary Lichtenstein Humanitarian AwardVoices Against Brain Cancer
  14. 2013
    Ohtli AwardGovernment of Mexico
  15. 2013
    Nifty Fifty ScientistUSA Science & Engineering Festival
  16. 2013
    Invited GuestLa Casa Cultural, Yale University
  17. 2012
    Doctor of Humane Letters: Honoris CausaLackawanna College
  18. 2012
    Honorary ProfessorInstituto Tecnologico de Monterrey, Mexico
  19. 2012
    International Latino Book AwardLatino Literacy Now
  20. 2012
    Immigrant Achievement AwardAmerican Immigration Council
  21. 2012
    Nifty Fifty ScientistUSA Science & Engineering Festival
  22. 2012
    2012 Chair's AwardCongressional Hispanic Caucus Institute
  23. 2012
    Super DoctorSuper Doctors
  24. 2011
    Martinez and Townsel Endowed LectureMarine Biology Laboratory
  25. 2011
    Friday Night LectureMarine Biological Laboratory
  26. 2011
    Top DocsBaltimore Magazine
  27. 2011
    Doctor of Human Letters: Honoris CausaSouthern Vermont College
  28. 2011
    Top 20 Lecturer in the Genes to Society curriculumJohns Hopkins University
  29. 2011
    Nifty Fifty ScientistUSA Science & Engineering Festival
  30. 2010
    Outstanding Alumni AwardAmerican Association of Community Colleges
  31. 2010
    Featured in the Aetna Hispanic Heritage CalendarAetna Foundation
  32. 2010
    Health Care Heroes finalistMaryland Daily Record
  33. 2010
    Nifty Fifty ScientistUSA Science & Engineering Festival
  34. 2009
    Distinguished Alumni AwardCalifornia Community College
  35. 2009
    Top Ten Abstracts - "Disparities in Referral to Neuro-Oncological Surgery in the United States"Congress of Neurological Surgeons
  36. 2009
    Top Ten Abstracts - “Is There a Gender Difference in Mortality Risk Among Traumatic Brain Injury Patients?”Congress of Neurological Surgeons
  37. 2009
    1st Place AANS History SectionAmerican Association of Neurological Surgeons
  38. 2008
    Davenport Fellowship AwardMayo Clinic
  39. 2008
    Public Service Citation for outstanding work with medical students and neurosurgical residentsAmerican Association of Neurological Surgeons
  40. 2008
    Levi Watkins LectureVanderbilt University
  41. 2008
    Invited Guest at Harvard with Peter Black Cancer LectureHarvard Medical School
  42. 2008
    Honorary ProfessorUniversity of the Americas
  43. 2008
    Honorary ProfessorUniversity of the Americas
  44. 2008
    AANS Bittner AwardAmerican Association of Neurological Surgeons
  45. 2008
    National Leadership in Science and Medicine AwardMerage Foundations
  46. 2008
    2008 Health Care Heroes Finalist Breakfast AwardMaryland Daily Record
  47. 2008
    Synthes Skull Base AwardTumor Section, American Association of Neurological Surgeons/Congress of Neurological Surgeons
  48. 2008
    2008 Safeway Hispanic Heritage Month AwardSafeway
  49. 2008
    America’s Role Model AwardOlender Foundation
  50. 2007
    Richard J. Otenasek, Jr, Faculty Teaching AwardDepartment of Neurosurgery, Johns Hopkins Hospital
  51. 2007
    Robert Wood Johnson Foundation AwardRobert Wood Johnson Foundation
  52. 2007
    Brilliant 10 Scientists AwardPopular Science Magazine
  53. 2007
    US Top DocsBaltimore Magazine
  54. 2007
    Top 100 Most Influential Hispanics in the U.S.Hispanic Business Journal
  55. 2006
    “Hall of Fame” InductionHispanic Scholarship Fund
  56. 2006
    NIH Loan Repayment ProgramNational Institutes of Health
  57. 2006
    Marquis Who's Who in America, 60th EditionMarquis Who's Who
  58. 2006
    Marquis Who's Who in Science and Engineering, 8th EditionMarquis Who's Who
  59. 2006
    Marquis Who's Who in the World, 23rd EditionMarquis Who's Who
  60. 2006
    Marquis Who's Who in Finance and Business, 35th EditionMarquis Who's Who
  61. 2006
    NIH Mentored Clinician Scientist AwardNational Institutes of Health
  62. 2006
    Physician-Scientist Career AwardHoward Hughes Medical Institute
  63. 2006
    Career Development AwardAmerican Society of Clinical Oncology Cancer Foundation
  64. 2006
    Franklin Martin Faculty Research AwardAmerican College of Surgeons
  65. 2006
    Passano Physician Scientist AwardJohns Hopkins University
  66. 2006
    Lorenz Surgical Young Clinician Investigator AwardAmerican Association of Neurological Surgeons
  67. 2005
    Howard Naffziger Neurological Surgery Resident AwardUniversity of California San Francisco
  68. 2005
    Marquis Who's Who in the World, 22nd EditionMarquis Who's Who
  69. 2005
    Edwin Boldrey Science Award57th Annual Meeting
  70. 2004
    Alpha Omega Alpha Medical Honor SocietyUniversity of California San Francisco
  71. 2004
    Marquis Who's Who in Science and Engineering, 7th EditionMarquis Who's Who
  72. 2004
    Marquis Who's Who in Finance and Business, 34th EditionMarquis Who's Who
  73. 2004
    AANS Bittner AwardAmerican Association of Neurological Surgeons
  74. 2004
    AANS Journal of Neurooncology AwardAmerican Association of Neurological Surgeons
  75. 2003
    Class of 2003 Annual Clinical Teaching AwardUniversity of California San Francisco
  76. 2003
    Commendation AwardSan Francisco Police Department
  77. 2003
    Appreciation AwardCity of San Francisco
  78. 2003
    Edwin Boldrey Science Award55th Annual Meeting
  79. 2003
    First Place, Region IX Resident Paper CompetitionAmerican College of Surgeons
  80. 2002
    Blue Ribbon Award for Poster PresentationCongress of Neurological Surgeons
  81. 2000
    Most Valuable Intern AwardUniversity of California San Francisco
  82. 1999
    Cum LaudeHarvard Medical School
  83. 1999
    Most Valuable InternSan Francisco General Hospital
  84. 1999
    Graduation Multiculturalism AwardHarvard Medical School
  85. 1999
    Ralph W. Ellison Graduation AwardNational Medical Fellowships
  86. 1999
    Honorable Mention AwardSigma Xi Research Society
  87. 1998
    Support towards Completion of Medical StudiesHoward Hughes Medical Institute
  88. 1998
    Listed in the Field of ScienceWho's Who
  89. 1996
    Featured in Dean’s Annual ReportHarvard Medical School
  90. 1994
    Highest HonorsUniversity of California Berkeley
  91. 1994
    Student Life Achievement AwardUniversity of California Berkeley
  92. 1994
    ScholarshipHarvard Medical School
  93. 1993
    Honor’s Research ScholarUniversity of California Berkeley
  94. 1992
    ScholarshipHispanic Scholarship Fund
  95. 1991
    Helen Danner Memorial ScholarshipSan Joaquin Delta College
  96. 1991
    Memorial & Student Association ScholarshipsSan Joaquin Delta College
  97. 1991
    ScholarshipUniversity of California Berkeley
  98. 1991
    Honor’s ListUniversity of California Berkeley
  99. 1990
    Debate Tournament, Second Place in Speaker PointsSan Jose State University
  100. 1990
    Outstanding Tutor Performance AwardSan Joaquin Delta College
  101. 1990
    President’s ListSan Joaquin Delta College
  102. 1973
    Alpha Omega AlphaAlpha Omega Alpha Honor Medical Society
  103. 1966
    NIH TraineeshipIowa State University
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Professional memberships

  1. 2014 - present
    MemberBoard of Scientific Counselors for Clinical Sciences and Epidemiology (BSC), National Cancer Institute
  2. 2011 - 2016
    FacultyTraining Advisory Committee, Research Training In Endocrinology, Johns Hopkins University School of Medicine
  3. 2011 - 2016
    Faculty MentorNeuroscience Academic Development Award, Johns Hopkins University School of Medicine
  4. 2011 - present
    MemberSociety of University Surgeons
  5. 2010 - 2011
    MemberKimmel Cancer Center Director Search Committee, Johns Hopkins Bayview Medical Center
  6. 2010
    Abstract ReviewerTumor Section, 78th Annual Meeting, American Association of Neurological Surgeons
  7. 2010 - present
    MemberThe Endocrine Society
  8. 2009 - 2016
    MemberCenter for Innovative Medicine Advisory Council, Johns Hopkins Medicine
  9. 2009 - present
    Co-ChairInternational Committee, Tumor Section, American Association of Neurological Surgeons/Congress of Neurological Surgeons
  10. 2008 - 2009
    MemberCommittee on Graduate Education, Johns Hopkins University School of Medicine
  11. 2008
    ChairTumor Section, Scientific Committee, Congress of Neurological Surgeons
  12. 2008 - present
    MemberSTEM Task Force, State of Maryland
  13. 2007
    Co-ChairAcademic Careers Symposium, Brain Tumor International Meeting, American Association of Neurological Surgeons/Congress of Neurological Surgeons
  14. 2007
    ChairSilent Auction of the Neurosurgery Research and Education Foundation, Young Neurosurgeons Committee, American Association of Neurological Surgeons
  15. 2007 - present
    MemberBrain Tumor Committee, American Association of Neurological Surgeons/Congress of Neurological Surgeons
  16. 2007 - present
    MemberAngels in the Operating Room; Advisory Board
  17. 2007 - present
    Executive Committee MemberBrain Tumor Committee, American Association of Neurological Surgeons/Congress of Neurological Surgeons
  18. 2006 - 2016
    FacultyTraining Advisory Committee, Summer Program in Neuroscience, Ethics, and Survival, Johns Hopkins University School of Medicine
  19. 2006 - 2016
    MemberTraining Advisory Committee, Diversity Program in Neuroscience, American Psychological Association
  20. 2006 - 2010
    MemberTraining Advisory Committee, Specialized Neuroscience Summer Research Program, Johns Hopkins University School of Medicine
  21. 2006 - 2007
    MemberNeurology Directorship Search Committee, Johns Hopkins Medicine
  22. 2006
    Vice ChairSilent Auction of the Neurosurgery Research and Education Foundation, Young Neurosurgeons Committee, American Association of Neurological Surgeons
  23. 2006 - present
    Young Faculty RepresentativeCouncil of State Neurosurgical Societies
  24. 2006 - present
    MemberAmerican College of Surgeons
  25. 2006 - present
    MemberAmerican Association for Cancer Research
  26. 2006 - present
    MemberAmerican Brain Tumor Association
  27. 2006 - present
    MemberAmerican Society for Clinical Oncology
  28. 2006 - present
    MemberMedChi, The Maryland State Medical Society
  29. 2005 - 2016
    FacultyTraining Advisory Committee, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine
  30. 2005 - present
    MemberNeuro-Oncology Fellowship Committee, Johns Hopkins University School of Medicine
  31. 2003 - 2004
    Resident RepresentativeCouncil of State Neurosurgical Societies
  32. 2002 - present
    MemberYoung Neurosurgeons Committee, American Association of Neurological Surgeons
  33. 2001 - present
    MemberAmerican Association of Neurological Surgeons
  34. 2001 - present
    MemberCongress of Neurological Surgeons
  35. 2001 - present
    MemberTumor Section, American Association of Neurological Surgeons/Congress of Neurological Surgeons
  36. 2001 - present
    MemberPediatric Neurosurgery Section, American Association of Neurological Surgeons/Congress of Neurological Surgeons
  37. 2000 - 2003
    MemberGraduate Medical Education Committee, University of California San Francisco
  38. 1999 - present
    MemberDevelopment Policy Committee, Mayo Clinic Committees
  39. 1999 - present
    MemberSigma Xi Research Society
  40. 1998 - 2000
    MemberMayo Clinic Health System in Austin, Mayo Clinic Health System
  41. 1998 - present
    MemberAmerican Association for the Advancement of Science
  42. 1998 - present
    MemberSociety for Experimental Biology and Medicine
  43. 1997 - 1999
    Student Coordinator and LiaisonPrematriculation Biomedical Research Program, Harvard Medical School
  44. 1997 - 1999
    MemberClinical Research Subcommittee, Research Committee, Mayo Clinic Rochester - Executive Board
  45. 1997 - present
    MemberResearch Committee, Mayo Clinic Rochester - Executive Board, Mayo Clinic Rochester Committees
  46. 1997 - present
    MemberFiscal Research Subcommittee, Research Committee, Mayo Clinic Rochester - Executive Board
  47. 1997 - present
    MemberResearch Executive Committee, Mayo Clinic Committees
  48. 1997 - present
    MemberBoston Area Neuroscience Group
  49. 1997 - present
    MemberAssociation for Ethnic Diversity in the Neurosciences
  50. 1996 - present
    MemberMassachusetts Medical Society
  51. 1996 - present
    MemberAmerican Medical Association
  52. 1995 - 1999
    Student Coordinator and LiaisonHinton-Wright Biomedical Research Society, Harvard Medical School
  53. 1994 - present
    Pfeiffer FellowHinton-Wright Biomedical Research Society, Harvard Medical School
  54. 1994 - present
    MemberNational Chicano Health Organization
  55. 1993 - 1994
    Co-ChairLatinos in Health and Education, University of California Berkeley
  56. 1993
    MemberCommittee on Diversity, National Academy of Sciences
  57. 1993 - present
    MemberSociety of Neuroscience
  58. 1993 - present
    MemberSociety for the Advancement of Chicanos and Native Americans in Science
  59. 1988 - 1990
    MemberInstitutional Animal Care and Use Committee, Mayo Clinic Committees
  60. 1982 - 1984
    MemberEmergency Care Committee, Mayo Clinic Committees
  61. 1982 - 1983
    MemberMayo Clinic Research Committee, Mayo Clinic Committees
  62.  
    FellowAmerican Academy of Otolaryngology - Head and Neck Surgery
  63.  
    FellowAmerican Academy of Facial Plastic and Reconstructive Surgery
  64.  
    FellowAmerican College of Surgeons
  65.  
    MemberAmerican Rhinologic Society
  66.  
    MemberThird Year Curriculum Committee, Mayo Medical School, Mayo Clinic College of Medicine and Science
  67.  
    MemberPractice Committee, Division of Area General Internal Medicine, Department of Internal Medicine
  68.  
    MemberResearch Committee, Division of General Internal Medicine, Department of Internal Medicine
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Publications

Research activities

See a description of research activities.