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Mark V. Larson, M.D.

  1. Gastroenterologist
  2. Internist

Mark V. Larson, M.D., is a consultant in the Division of Gastroenterology and Hepatology at Mayo Clinic in Rochester, Minnesota, where he has provided care to patients since 1989. Dr. Larson specializes in the diagnosis and treatment of gastrointestinal disorders, with a clinical practice focused on colorectal neoplasia and complex endoscopic procedures. He directs Mayo Clinic's gastrointestinal endoscopy practice and offers comprehensive care to people from around the world.

In addition to his clinical role, Dr. Larson is an accomplished educator and researcher. He has mentored numerous trainees and contributed extensively to advancing colorectal cancer prevention and endoscopic innovation through publications, clinical trials, and patents.

Areas of expertise

Dr. Larson delivers personalized care using advanced endoscopic techniques to diagnose and manage gastrointestinal conditions. His clinical areas of expertise include:

  • Malignant and premalignant conditions of the stomach, gastrointestinal tract, and colon: Comprehensive evaluation and treatment strategies
  • Hereditary gastrointestinal syndromes: Care for familial adenomatous polyposis (FAP) and hereditary nonpolyposis colorectal cancer (Lynch syndrome)
  • Routine endoscopic procedures: Colonoscopy, upper endoscopy, and enteral feeding tube placement
  • Advanced interventional endoscopy: Complex and emergency procedures, including management of active gastrointestinal bleeding
  • Colorectal cancer screening and prevention: Adenoma detection, surveillance protocols, and chemoprevention research
  • Radiation proctopathy and mucosal disorders: Endoscopic management of treatment-related complications

Research and expertise

Dr. Larson's research focuses on colorectal cancer prevention, including chemoprevention of adenomatous polyps, and improving outcomes through advanced endoscopic techniques. He has served as principal investigator for multiple clinical trials and is co-inventor on patents for chemoprevention of colorectal polyps. His academic leadership includes his role as Associate Professor of Medicine and director of endoscopy practice at Mayo Clinic. He is board certified in internal medicine and gastroenterology and holds Silver Level Certification in quality improvement through Mayo Clinic Quality Academy.

  1. Endoscopic procedure
  2. Upper endoscopy
  • Adenomatous colorectal polyps
  • Colon and rectal cancer
  • Endoscopic removal of large colorectal polyps
  • Advanced therapeutic endoscopy
  • Endoscopic treatment of gastrointestinal bleeding
  1. 1989
    ResidentGastroenterology, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  2. 1989
    Fellow - GastroenterologyMayo Graduate School of Medicine, Mayo Clinic College of Medicine
  3. 1986
    ResidentInternal Medicine, Programs in Rochester, Mayo School of Graduate Medical Education, Mayo Clinic College of Medicine
  4. 1985
    Resident - Internal MedicineMayo Graduate School of Medicine, Mayo Clinic College of Medicine
  5. 1982
    MDCarver College of Medicine, University of Iowa
  6. 1978
    BALuther College

Certifications

  1. 1989
    GastroenterologyAmerican Board of Internal Medicine
  2. 1985
    Internal MedicineAmerican Board of Internal Medicine

Awards and honors

  1. 2012
    Excellence in TeachingDepartment of Internal Medicine
  2. 2004
    Excellence in Teaching AwardMayo Medical School, Mayo Clinic College of Medicine and Science, Department of Education Administration
  3. 2003
    Excellence in Teaching AwardMayo Medical School, Mayo Clinic College of Medicine and Science, Department of Education Administration
  4. 2002
    Teacher of the Year for Non-Surgical FacultyDepartment of Surgery
  5. 2002
    Excellence in Teaching AwardMayo Medical School, Mayo Clinic College of Medicine and Science, Department of Education Administration
  6. 2002
    Audiovisual Image AwardAmerican College of Rheumatology
  7. 2001
    Excellence in Teaching AwardMayo Medical School, Mayo Clinic College of Medicine and Science, Department of Education Administration
  8. 1989
    William J. Summerskil Award for Excellence in ResearchMayo Clinic
  9. 1989
    J. Arnold Bargen Award for Excellence in GastroenterologyMayo Clinic
  10. 1988
    Glaxo Fellows' Research AwardAmerican College of Gastroenterology
  11. 1978
    Magna Cum LaudeLuther College
  12. 1978
    Postgraduate ScholarshipNational Collegiate Athletic Association (NCAA)
  13. 1977
    Munson Family ScholarshipLuther College

Professional memberships

  1. 2011 - present
    MemberPractice Convergence Council, Mayo Clinic Clinical Practice Committee, Mayo Clinic Committees
  2. 2011 - present
    ChairMayo Clinic Tagging and Tracking Subcommittee, Practice Convergence Council, Mayo Clinic Clinical Practice Committee
  3. 2008 - 2010
    MemberMayo Clinic Marketing Committee, Mayo Clinic Committees
  4. 2007 - present
    ChairFinance Executive Committee, Division of Gastroenterology and Hepatology, Department of Internal Medicine
  5. 2007 - present
    ChairFinance Committee, Division of Gastroenterology and Hepatology, Department of Internal Medicine
  6. 2007 - present
    MemberPractice Management and Economics Committee, American Gastroenterological Association
  7. 2005 - 2007
    Associate ChairFinance Committee, Division of Gastroenterology and Hepatology, Department of Internal Medicine
  8. 2005 - present
    MemberExecutive Committee, Division of Gastroenterology and Hepatology, Department of Internal Medicine
  9. 2005 - present
    MemberGI Integrated Finance Committee, Finance Committee, Division of Gastroenterology and Hepatology
  10. 2003 - 2012
    Liaison PhysicianMayo Regional Health System Committee, Department of Internal Medicine
  11. 2003 - 2007
    MemberMayo Outreach Oversight Committee, Outreach, Department of Internal Medicine
  12. 2003 - present
    Board MemberHope Lodge, American Cancer Society
  13. 2003 - present
    MemberOlmsted County, American Cancer Society
  14. 2001 - 2012
    MemberMayo Regional Health System Committee, Department of Internal Medicine
  15. 1999 - present
    MemberMinnesota Colorectal Cancer Consortium, Minnesota Department of Health
  16. 1997 - present
    MemberOncology, Abstract Selection Committee, American Gastroenterological Association
  17. 1997 - 2000
    MemberAbstract Selection Committee, American Gastroenterological Association
  18. 1995 - 2000
    MemberExecutive Committee, Division of Gastroenterology and Hepatology, Department of Internal Medicine
  19. 1995 - present
    MemberPractice Committee, Division of Gastroenterology and Hepatology, Department of Internal Medicine
  20. 1994 - 2007
    ChairGI Outreach Committee, Division of Gastroenterology and Hepatology, Department of Internal Medicine
  21. 1994 - 2007
    MemberGI Outreach Committee, Division of Gastroenterology and Hepatology, Department of Internal Medicine
  22. 1994 - present
    MemberInstitute for Clinical Systems Improvement
  23. 1994 - present
    MemberColorectal Cancer Screening Guidelines, Institute for Clinical Systems Improvement
  24. 1991 - 2000
    MemberGI Training/GI Education Committee, Division of Gastroenterology and Hepatology, Department of Internal Medicine
  25. 1991 - 1996
    ChairRotation for Internal Medicine Residents, Division of Gastroenterology and Hepatology, Department of Internal Medicine
  26. 1991 - 1996
    MemberRotation for Internal Medicine Residents, Division of Gastroenterology and Hepatology, Department of Internal Medicine
  27. 1991 - 1996
    MemberEducation Committee, Department of Internal Medicine
  28. 1991 - 1993
    MemberDevelopment Liaison Committee, Mayo Clinic Rochester Committees
  29. 1991 - 1993
    MemberInternal Medicine Residency Task Force, Department of Internal Medicine
  30. 1991 - 1992
    MemberPreventive Care Guidelines Task Force, Mayo Clinic Rochester Task Forces
  31. 1990 - present
    MemberAmerican Society for Gastrointestinal Endoscopy
  32. 1990 - present
    MemberAmerican College of Gastroenterology
  33. 1989 - present
    MemberAmerican Medical Association
  34. 1989 - present
    MemberMinnesota Medical Association
  35. 1989 - present
    MemberZumbro Valley Medical Society, Minnesota Medical Association
  36. 1989 - present
    MemberAmerican Gastroenterological Association
  37. 1988 - 1989
    Fellows' RepresentativeEducation Committee, Division of Gastroenterology and Hepatology, Department of Internal Medicine
  38. 1988 - 1989
    MemberEducation Committee, Division of Gastroenterology and Hepatology, Department of Internal Medicine
  39. 1988 - 1989
    MemberPharmacy and Therapeutics Subcommittee - Rochester, Clinical Practice Committee - Rochester
  40. 1985 - 1986
    MemberLutheran Church Hospital, KarKar, Papua New Guinea

Publications