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姓氏首字母: T

  1. Mathew Thomas, M.B.B.S., M.D.

    Mathew Thomas, M.B.B.S., M.D.

    1. General Surgeon
    2. Cardiothoracic Surgeon
    1. Jacksonville, FL
    擅长领域:

    Lung transplant, VATS, Pectus excavatum surgery, Chest surgery, Fundoplication, Esophagectomy, Robotic surgery, Diaphra...gm pacing, Nuss procedure, Hyperhidrosis surgery, Decortication, Chest wall resection, Tracheal resection, Tracheobronchoplasty, Extrapleural pneumonectomy, Diaphragm plication, Esophageal diverticulectomy, Ivor Lewis esophagectomy, Hiatal hernia, Achalasia, Pectus excavatum, Lung cancer, Mesothelioma, Tracheobronchomalacia, Hyperhidrosis, Myasthenia gravis, Tracheal stenosis, Esophageal cancer, Diaphragmatic hernia, Zenker's diverticulum, Diaphragm paralysis, Sarcoma, Carcinoid tumor, Solitary fibrous tumor, Mediastinal tumor, Schwannoma, Thymic tumor, Tracheomalacia, Chest wall deformity

研究

Research at Mayo Clinic is focused on understanding how pectus excavatum affects heart and lung function and whether surgical correction produces measurable improvements in patients' cardiopulmonary health. Mayo researchers conduct studies looking at long-term outcomes after Nuss repair, including investigations of exercise capacity, cardiac performance, and symptom improvement following both surgery and subsequent bar removal. The research aims to provide objective evidence of the physiologic benefits of repair beyond cosmetic correction.

In addition to studying long-term outcomes, Mayo Clinic investigators are working to improve the safety and effectiveness of pectus excavatum treatment. Research projects examine cardiac changes before and after repair, genetic factors that may contribute to pectus deformities, and strategies for optimizing postoperative pain management. They also focus on improving surgical outcomes by developing techniques to reduce pectus bar displacement, one of the most significant complications associated with the Nuss procedure. Mayo researchers also are exploring related conditions, including autonomic dysfunction and exercise intolerance in patients with pectus excavatum. Their research helps expand understanding of how the condition affects overall health and quality of life.

Publications

See a list of publications about the Nuss procedure by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Research Profiles

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Oct. 07, 2026
  1. Brussels AR, et al. Perioperative considerations in anesthesia for minimally invasive repair of pectus excavatum, Nuss procedure. Seminars in Pediatric Surgery. 2024; doi:10.1016/j.sempedsurg.2024.151459.
  2. Cameron JL, et al., eds. Management of pectus excavatum. In: Current Surgical Therapy. 15th ed. Elsevier; 2026. https://www.clinicalkey.com. Accessed Sept. 10, 2026.
  3. Mohamed JS, et al. Quality of life with minimally invasive repair of pectus excavatum: A systematic review and meta-analysis. Annals of Translational Medicine. 2023; doi:10.21037/atm-23-1647.
  4. Huerta CT, et al. Outcomes after pectus excavatum repair: A nationwide comparison of Nuss versus Ravitch operations. Journal of Surgical Research. 2024; doi:10.1016/j.jss.2024.09.025.
  5. Dunning J, et al. The pectus care guidelines: Best practice consensus guidelines from the joint specialist societies SCTS/MF/CWIG/BOA/BAPS for the treatment of patients with pectus abnormalities. European Journal of Cardio-Thoracic Surgery. 2024; doi:10.1093/ejcts/ezae166.
  6. Mayer OH. Pectus excavatum: Treatment. https://www.uptodate.com/contents/search. Accessed Sept. 4, 2026.
  7. Rshaidat H, et al. Complication rate of the Nuss procedure in adults and pediatric patients: National database analysis. Annals of Thoracic Surgery Short Reports. 2024; doi:10.1016/j.atssr.2024.04.013.
  8. Van Polen EJ, et al. Postoperative pain management after minimally invasive repair of pectus excavatum: A systematic review and network meta-analysis. Journal of Pediatric Surgery. 2025; doi:10.1016/j.jpedsurg.2025.162282.
  9. Coorens NA, et al. Advancements in preoperative imaging of pectus excavatum: A comprehensive review. Journal of Thoracic Disease. 2024; doi:10.21037/jtd-23-662.
  10. Wang C, et al. Age-stratified outcomes of the Nuss procedure for pectus excavatum: Challenging the association between younger age and inferior correction. Annals of Thoracic Surgery. 2026; doi:10.1016/j.athoracsur.2026.07.022.
  11. Marques D, et al. Intercostal nerve cryoablation for postoperative pain control after the Nuss procedure in children: A systematic review and meta-analysis. European Journal of Pediatric Surgery. 2026; doi:10.1055/a-2708-2796.

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