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The purpose of phase 1 of this trial is to determine the maximum tolerated dose of temozolomide followed by selinexor in recurrent glioblastoma patients as ...
Patients will be randomized 1:1 into the two arms. Patients randomized to GDC-0199+R will be given GDC-0199 daily (oral, target dose 400 mg) and will ...
The purpose of this study is to determine the quality of life scores for patients that have undergone subtotal petrosectomy and ear canal closure for ...
Rochester, Minn. This is a survey study to describe how women with Lynch syndrome are being screened for gynecologic cancer risk, their perception of cancer ...
The purpose of this study is to describe a practical and reproducible radiographic view that can be used in the work-up of ulnocarpal impaction. Aggressive ...
Rochester, Minn. The purpose of this interventional study is to test and compare the effectiveness of two elimination diets—the 1-food elimination diet (1FED, ...
Selumetinib is a drug that works by blocking some enzymes that low grade glioma tumor cells need for their growth. This results in killing tumor cells. Drugs ...
1. Adults age 18 years or older. 2. Olmsted County residents at the time of study entry. Exclusion criteria: 1. Pediatric population (age<18). 2. Unwilling to ...
Research is instrumental for improving medical care and the patient experience. Finding new surgical techniques can create better outcomes and minimize ...
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