Orthopedic Surgery

下面列出了当前开展的临床试验。

根据地点、状态和其他条件对此研究列表进行过滤。

1. A Study to Evaluate Manipulation Under Anesthesia After Bilateral Primary Total Knee Arthroplasty

   Rochester, Minn.

   The purpose of this study is to determine unique genetic profile of patients requiring MUA following bilateral pTKA via genetic sequencing, to determine outcomes of patients receiving MUA in terms of KSS, implant durability, survival free of reoperation, and to define characteristics and comorbidities of patients undergoing unilateral and bilateral MUA.

2. A Study to Evaluate Awake vs. Asleep Spine Surgery

   Jacksonville, Fla.

   Patients undergoing spine lumbar surgery will be asked to perform short exams/questionnaires aimed at determining cognitive function, quality of life, health outcomes twice post surgery with a baseline performance prior to surgery.

3. Detection of Infection in Arthroplasty

   Rochester, Minn.

   The purpose of this study is to determine the sensitivity, specificity, positive and negative predictive values of molecular detection of microorganisms, detection of microbial proteins and antibodies against microorganisms, and inflammatory markers (e.g., leukocyte esterase, CRP) in synovial fluid for the diagnosis of prosthetic joint infection (PJI).

4. A Study to Validate the Patient-Specific Functional Survey in Patients with Carpal Tunnel Syndrome

   Rochester, Minn.

   The purpose of this study is to determine if the Patient-Specific Functional Survey (PSFS) is a valid and reliable measure to evaluate functional difficulties with carpal tunnel syndrome.

5. 3D US Imaging of Acute Nerve Root Avulsions in Injuries of the Brachial Plexus

   Jacksonville, Fla.

   The purpose of this study is to address a knowledge gap. Early diagnosis of nerve root avulsion injuries following brachial plexus trauma remain a barrier to the early treatment of these complex injuries.  Traditionally, an observation period of 6 months following brachial plexus injuries has been utilized to allow for reinnervation.  Reinnervation is not possible in the setting of nerve root avulsion from the spinal cord and waiting for reinnervation in this setting unnecessarily delays treatment and potentially compromises outcome.  Having the ability to provide a real time evaluation of nerve root integrity would obviate the need of other more expensive and complex advanced imaging such as CT/myelography, currently considered the good standard.

6. Spasticity After Spinal Cord Injury

   Rochester, Minn.

   A growing body of research demonstrates a correlation between residual corticospinal connectivity and severity of spasticity following SCI (Sangari et al., 2019b). The purpose of this study is to analyze this correlation to better understand the relationship between spasticity as a biomarker of residual corticospinal connectivity and neurologic and functional recovery.  

7. A Study to Survey Epidural User Experience for Individuals with Spinal Cord Injury Paralysis

   Rochester, Minn.

   This is a survey study to identify user-reported motor, sensory, and autonomic functions that are enabled by epidural stimulation, establish correlations between epidural stimulation usage, rehabilitation, functional gains, and user experience in the laboratory and community settings, and to understand and identify subjective goals, benefits, and barriers that still exist with implanted epidural stimulator community.

8. A Study to Assess the Effect of Radial Deviation on the Pronated Grip

   Rochester, Minn.

   The purpose of this study is to describe a practical and reproducible radiographic view that can be used in the work-up of ulnocarpal impaction.

9. Outcome of Capsular Release for Elbow Contracture

   Rochester, Minn.

   The purpose of this study is to assess the outcome and complications of capsular release for elbow contractures.

    

10. The Effects of Prophylactic Limited Palmar Fasciectomy on Surgical Outcomes and Scarring

    Rochester, Minn.

    Research is instrumental for improving medical care and the patient experience. Finding new surgical techniques can create better outcomes and minimize recovery time and complications for patients. Some patients undergoing trigger finger surgery with a pre-existing Dupuytren's cord may develop a thickened surgical scar after surgery, which can cause discomfort, difficulty with moving or using, and other complications in the affected finger(s) or hand. The investigator is investigating a surgical technique to minimize these potential complications and scarring after surgery. Subjects are being asked to take part in this research study because they have been diagnosed with trigger finger and pretendinous Dupuytren's cord and have decided to undergo surgery rather than try medical treatment.