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Your doctor will check you closely while you are receiving this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to receive it. Blood tests may be needed to check for unwanted effects.

This medicine may cause a serious type of allergic reaction called anaphylaxis, which can be life-threatening and requires immediate medical attention. Call your doctor right away if you have a rash, hives, itching, dizziness, swelling of your hands, face, mouth, or tongue, trouble breathing or swallowing, or chest pain after you receive the medicine.

This medicine may cause infusion reactions, including rash, itching, or redness of the skin, difficulty with breathing, feeling of warmth or redness of the face, neck, arms, and occasionally, upper chest, or chest discomfort or pain while you are receiving the injection or within 2 hours after you receive it. Tell your doctor or nurse right away if you have any of these symptoms.

Patients of African, Mediterranean, or Southern Asian ancestry are at higher risk of serious side effects and should be carefully evaluated by their doctor before starting this medicine.

Gout flares may occur in the first 3 months when you start receiving this medicine. Do not stop receiving this medicine even if you have a gout flare. Your doctor may give you medicines (eg, colchicine, non-steroidal antiinflammatory drug or NSAID) to reduce and prevent worsening of the gout.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.