Precautions
Drug information provided by: Merative, Micromedex®
It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Blood tests may be needed to check for unwanted effects. Your dose may be reduced, or the medicine withheld or stopped, if certain side effects occur.
Using this medicine while you are pregnant can harm your unborn baby. It may also cause birth defects if the father is using it when his sexual partner becomes pregnant. If you are a woman who can get pregnant, your doctor may do tests to make sure you are not pregnant before starting treatment. Female patients should use effective birth control during treatment and for at least 6 weeks after the last dose. Male patients who have female partners should use effective birth control during treatment and for at least 4 months after the last dose. If you think you or your partner becomes pregnant while using the medicine, tell your doctor right away.
If you plan to have children, talk with your doctor before using this medicine. Some men and women using this medicine have become infertile (unable to have children).
This medicine may cause swelling of the lungs (pneumonitis) or interstitial lung disease. These are life-threatening conditions and require immediate medical attention. The symptoms may be similar to the symptoms from lung cancer. Check with your doctor right away if you have new or worsening cough, fever, or trouble breathing.
Contact your doctor right away if you have any changes to your heart rhythm. You might feel dizzy or faint, or you might have a slow, fast, pounding, or uneven heartbeat.
This medicine may cause heart problems. Tell your doctor right away if you have fast, pounding, or uneven heartbeat, lightheadedness, trouble breathing, or swelling of your ankles or feet.
Check with your doctor right away if you have any changes to your eyes, such as eye pain or redness, or vision changes while you are using this medicine. Your doctor may want you to have your eyes checked by an eye doctor (ophthalmologist).
Serious skin reactions (eg, Stevens-Johnson syndrome, erythema multiforme, and toxic epidermal necrolysis) can occur with this medicine. Check with your doctor right away if you have blistering, peeling, or loosening of the skin, chills ,cough, diarrhea, joint pain, red irritated eyes, red skin lesions, severe acne or skin rash, sore throat, sores or ulcers on the skin, or fever or chills while you are using this medicine.
This medicine may cause cutaneous vasculitis (swelling of the blood vessels in the skin). Check with your doctor right away if you have blisters on the skin, purple spots or redness of the skin that does not fade when pressed on the lower arms, lower legs, or buttocks, or large hives on the trunk that do not go away within 24 hours and look bruised.
Check with your doctor right away if you have chest pain or tightness, chills, cough, fever, headache, sores, ulcers, or white spots in the mouth, swollen or painful glands, trouble breathing, unusual bleeding or bruising, or unusual tiredness or weakness. These maybe symptoms of a blood problem (eg, aplastic anemia).
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Portions of this document last updated: April 01, 2024
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