Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

  1. Anxiety
  2. bloating or swelling of the face, arms, hands, lower legs, or feet
  3. burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  4. confusion
  5. decrease in urine volume
  6. difficulty in breathing or swallowing
  7. difficulty in passing urine (dribbling)
  8. fast, irregular, pounding, or racing heartbeat or pulse
  9. painful urination
  10. rapid weight gain
  11. seeing, hearing, or feeling things that are not there
  12. skin itching, rash, or redness
  13. swelling of the face, throat, or tongue
  14. tremor
  15. unusual weight gain or loss
  16. upper stomach pain

Rare

  1. Bluish color of the fingernails, lips, skin, palms, or nail beds
  2. burning, itching, redness, skin rash, swelling, or soreness at the application site
  3. confusion about identity, place, and time
  4. false or unusual sense of well-being
  5. irregular, fast or slow, or shallow breathing

Incidence not known

  1. Agitation
  2. blurred vision
  3. chest pain or discomfort
  4. cough
  5. darkening of the skin
  6. diarrhea
  7. dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  8. fever
  9. headache
  10. hives
  11. lightheadedness, dizziness, or fainting
  12. loss of appetite
  13. mental depression
  14. nausea
  15. nervousness
  16. overactive reflexes
  17. poor coordination
  18. pounding in the ears
  19. restlessness
  20. severe constipation
  21. severe vomiting
  22. shivering
  23. sweating
  24. talking or acting with excitement you cannot control
  25. tightness in the chest
  26. unusual tiredness or weakness
  27. vomiting

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

  1. Cold, clammy skin
  2. drowsiness that is so severe you are not able to answer when spoken to or, if asleep, cannot be awakened
  3. pinpoint (small) pupils in the eyes
  4. seizures
  5. slow heartbeat
  6. very slow or troubled breathing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Constipation
  2. feeling cold
  3. sleepiness or unusual drowsiness
  4. trouble sleeping

Less common

  1. Dry mouth
  2. feeling of constant movement of self or surroundings
  3. feeling of crawling, tingling, or burning of the skin
  4. lack or loss of strength
  5. memory loss
  6. sensation of spinning
  7. unusual dreams

Rare

  1. Abnormal ejaculation
  2. decreased interest in sexual intercourse
  3. decreased sexual performance or desire
  4. inability to have or keep an erection
  5. loss in sexual ability, desire, drive, or performance
  6. muscle twitching

Incidence not known

  1. Belching
  2. heartburn
  3. indigestion
  4. stomach discomfort or upset

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Portions of this document last updated: Nov. 01, 2023