高草酸尿症和草酸盐沉着症

Sept. 24, 2026

研究

妙佑医疗国际通过其位于明尼苏达州罗切斯特的妙佑医疗国际高草酸尿症中心和罕见肾结石联合会,在多个领域积极开展高草酸尿症研究。该中心对高草酸尿症患者数据的国际注册登记项目进行维护、汇编结果统计数据并维护用于调查和合作研究的尿液、血浆、血液和肝脏样本库。

该中心为人们提供参与临床试验的机会,以测试新的诊断和治疗方法。

正在进行的研究项目包括:

  • 使用主动患者注册登记项目来增强对原发性和肠源性高草酸尿症这两种疾病的理解。
  • 在原发性高草酸尿症和其他基因导致的肾结石病或肾钙质沉着症中进行基因变异鉴定,也称为基因突变,包括将基因变异与疾病结果进行相关性分析。
  • 评估原发性高草酸尿症的新治疗方法,包括使用新型药物,例如能够阻止肝脏中草酸合成的小分子抑制性 RNA。
  • 评估肠源性高草酸尿症的新治疗方法,包括口服草酸降解酶和细菌等药物治疗。
  • 饮食和钙摄入量对尿草酸水平影响的评估
  • 使用计算机断层成像(CT)扫描检测肾结石类型的新技术开发以及使用泌尿外科器械将其粉碎的能力。
  • 原发性高草酸尿症患者和其他肾结石患者的生活质量改善。

著述

请参阅美国国家医学图书馆检索服务系统 PubMed 所收录的妙佑医疗国际医生在高草酸尿症领域的著述目录。

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