心血管医学

以下为当前的临床试验。

按院区、状态和其他条件筛选该研究列表。

1. Echocardiographic Measures of Pulmonary Vascular Distensibility and Effects on Lung Diffusing Capacity

   Rochester, Minn.

   The purpose of this study is to determine if the change in pulmonary vascular compliance with positional changes (upright, supine, and Trendelenburg position) is different in younger versus older individuals.

2. Prevalence of Transthyretin Cardiac Amyloidosis in Clinically Significant Aortic Stenosis

   Rochester, Minn.

   The purpose of this study is to determine the prevalence of TTR-CA in a community-based cohort of moderate and severe aortic stenosis patients using 99mTc-PYP single-photon positive emission computed tomography with computed tomography (SPECT/CT).

3. A Study to Evaluate Potential Myocardial Injury Following Magnetic Resonance Imaging (MRI)

   Rochester, Minn.

   The purpose of this study is to prospectively determine if magnetic resonance imaging (MRI) in patients with cardiac implantable electronic devices (CIED) results in myocardial injury as assessed by changes in high sensitivity cardiac troponin T (hs-cTnT) assay. This will be done by comparing pre-and-post MRI hs-cTnT levels in these patients.

4. Invasive and Noninvasive Assessments of Myocardial Elasticity

   Rochester, Minn.

   The purpose of this study is to assess the correlation between myocardial elasticity (ME) measurements obtained simultaneously during cardiac hemodynamic catheterization and intraprocedural echocardiography.

5. Study of Awareness and Detection of Familial Hypercholesterolemia (CASCADE-FH)

   Rochester, Minn.

   The CASCADE Familial Hypercholesterolemia Registry will track therapy, clinical outcomes, and patient-reported outcomes over time aiming to increase familial hypercholesterolemia awareness, promote optimal disease management, and improve outcomes. This study is not recruiting family members of FH patients at this time.

6. A Study of the Effect of Myectomy on the Sudden Cardiac Death Risk in Hypertrophic Cardiomyopathy

   Rochester, Minn.

   The primary purpose/objective of this study is to determine whether myectomy as a management option for severe hypertrophic cardiomyopathy (HCM) reduces the incidence of sudden cardiac death.

7. Bioengineered Cardiac Tissue for Hypoplastic Left Heart Syndrome Analysis

   Rochester, Minn.

   The purpose of this study is to produce and characterize patient-specific cardiac tissue for Hypoplastic Left Heart Syndrome (HLHS) using reprogrammed cell technology.

8. A Study to Evaluate the Burden of Treatment and Illness in Advanced Heart Failure Patients

   Rochester, Minn.

   The primary purpose of this study is to identify which aspects of treatment are most prevalent and burdensome to patients with advanced heart failure.

9. Spontaneous Coronary Artery Dissection: Mechanistic Evaluation

   Rochester, Minn.

   The purpose of this study is to screen for unique or characteristic circulating peptides, hormonal biomarkers and circulating mRNA in patients who have experienced spontaneous coronary artery dissection (SCAD).

    

10. A Study to Analyze Association of Frequent Premature Ventricular Complex with Stroke or Transient Ischemic Attack

    Rochester, Minn.

    The purpose of this study is to verify that high Premature Ventricular Complex (PVC) burden is associated with increased risk of stroke and/or Transient Ischemic Attack (TIA), to examine outcomes such as stroke/TIA, atrial fibrillation/flutter, and all-cause mortality associated with PVCs, and to evaluate whether PVCs are associated with development of appendage dysfunction.