Which vaccines during pregnancy are recommended and which ones should I avoid?
Answer From Yvonne Butler Tobah, M.D.
Generally, vaccines that contain killed (inactivated) viruses can be given during pregnancy. Vaccines that contain live viruses aren't recommended for pregnant women.
Two vaccines are routinely recommended during pregnancy:
- Flu (influenza) shot. The flu shot is recommended for women who are pregnant during flu season. The flu shot is made from an inactivated virus, so it's safe for both you and your baby. Avoid the influenza nasal spray vaccine, which is made from a live virus.
- Tetanus toxoid, reduced diphtheria toxoid and acellular pertussis (Tdap) vaccine. One dose of Tdap vaccine is recommended during each pregnancy to protect your newborn from whooping cough (pertussis), regardless of when you had your last Tdap or tetanus-diphtheria (Td) vaccination. Ideally, the vaccine should be given between 27 and 36 weeks of pregnancy.
Getting the flu shot and the Tdap vaccine during pregnancy can protect you from infection and can also help protect your baby after birth before he or she can be vaccinated. This is important because the flu and whooping cough can be particularly dangerous for infants.
If you're at increased risk of certain infections, your health care provider might also recommend other vaccines during pregnancy — such as the hepatitis B vaccine.
Your health care provider will recommend avoiding vaccines that contain live viruses during pregnancy because they pose a theoretical risk. Examples of vaccines to avoid during pregnancy include:
- Chickenpox (varicella) vaccine
- Measles, mumps and rubella (MMR) vaccine
- Shingles vaccine
If you're planning a pregnancy, talk to your health care provider about any vaccines you might need beforehand.
Yvonne Butler Tobah, M.D.
Feb. 26, 2020
- AskMayoExpert. Vaccination before, during, and after pregnancy. Mayo Clinic; 2019.
- Pregnancy and vaccination. Centers for Disease Control and Prevention. https://www.cdc.gov/vaccines/pregnancy/pregnant-women/resources.html. Accessed Oct. 2, 2019.
- Recommended adult immunization schedule for ages 19 or older, United States, 2019. Centers for Disease Control and Prevention. https://www.cdc.gov/vaccines/schedules/hcp/index.html. Accessed Oct. 2, 2019.
- American College of Obstetricians and Gynecologists. Committee Opinion No. 718: Update on immunization and pregnancy: Tetanus, diphtheria, and pertussis vaccination. Obstetrics & Gynecology. 2017; doi:10.1097/AOG.0000000000002301. Reaffirmed 2019.
- Guidelines for vaccinating pregnant women. Centers for Disease Control and Prevention. https://www.cdc.gov/vaccines/pregnancy/hcp-toolkit/guidelines.html. Accessed Oct. 4, 2019.