Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

For all tetracyclines

More common
  1. Increased sensitivity of skin to sunlight (rare with minocycline)
  1. Abdominal pain
  2. bulging fontanel (soft spot on head) of infants
  3. headache
  4. loss of appetite
  5. nausea and vomiting
  6. visual changes
  7. yellowing skin

For demeclocycline only

Less common
  1. Greatly increased frequency of urination or amount of urine
  2. increased thirst
  3. unusual tiredness or weakness

For minocycline only

Less common
  1. Pigmentation (darker color or discoloration) of skin and mucous membranes

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For all tetracyclines

More common
  1. Cramps or burning of the stomach
  2. diarrhea
Less common
  1. Itching of the rectal or genital (sex organ) areas
  2. sore mouth or tongue

For minocycline only

More common
  1. Dizziness, light-headedness, or unsteadiness

In some patients tetracyclines may cause the tongue to become darkened or discolored. This effect is only temporary and will go away when you stop taking this medicine.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.