Proper Use

Drug information provided by: Merative, Micromedex®

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Take this medicine within 30 minutes after a moderate or high fat meal.

If you cannot swallow the capsule, you may open it and mix the contents in 30 milliliters (mL) of liquid (eg, milk, chocolate milk) or soft food (eg, apple sauce, yogurt). Take the mixture within 30 minutes after preparing it.

Keep using this medicine for the full treatment time, even if you feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (capsules):
    • For smallpox:
      • Adults and children weighing 120 kilograms (kg) or more—600 milligrams (mg) (3 capsules) taken 3 times a day for 14 days.
      • Adults and children weighing 40 kg to less than 120 kg—600 milligrams (mg) (3 capsules) taken 2 times a day for 14 days.
      • Children weighing 25 kg to less than 40 kg—400 mg (2 capsules) taken 2 times a day for 14 days.
      • Children weighing 13 kg to less than 25 kg—200 mg (1 capsule) taken 2 times a day for 14 days.
      • Children weighing less than 13 kg—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.