Proper Use

Drug information provided by: Merative, Micromedex®

A doctor or other trained health professional will give you this medicine. It is given as a shot under your skin, usually in the upper arm, stomach, or thighs once every 4 weeks for the first 3 doses, then once every 8 weeks.

Benralizumab injection may sometimes be given at home to patients who do not need to be in the hospital or clinic. If you are using this medicine at home, your doctor or nurse will teach you or your caregiver how to inject the medicine. Be sure that you understand exactly how to use this.

This medicine comes with a patient information leaflet. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.

If you use this medicine at home, you will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas. This will help prevent skin problems from the injections. Do not inject into scars, moles, or skin areas that are red, bruised, tender, hard, or not intact.

This medicine comes in two forms: a prefilled syringe (to be given by the doctor or other healthcare professional) and prefilled autoinjector or Fasenra® Pen™ (to be used by the patient or caregiver).

Allow 30 minutes for the prefilled autoinjector (Fasenra® Pen™) to warm up to room temperature. Do not warm it in any other way.

Use each Fasenra® Pen™ only one time. Do not save an open autoinjector.

Check the liquid in the Fasenra® Pen™. It should be clear and colorless or slightly yellow. Do not use this medicine if it is cloudy or if there are particles in it. Do not use the pen if it looks damaged or broken.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For injection dosage forms (prefilled syringe or prefilled autoinjector):
    • For severe asthma:
      • Adults and children 12 years of age and older—30 milligrams (mg) injected under your skin once every 4 weeks for the first 3 doses, then once every 8 weeks.
      • Children younger than 12 years of age—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store in the refrigerator. Do not freeze.

Protect this medicine from direct light. Do not shake. You may also keep an unopened carton at room temperature for up to 14 days. Throw away any medicine left out of the refrigerator for more than 14 days.

Throw away used syringes in a hard, closed container where the needles cannot poke through. Keep this container away from children and pets.