Ensayos clínicos A continuación se enumeran ensayos clínicos actuales.25 estudios en Otorrinolaringología (oído, nariz y garganta) y cirugía de cabeza y cuello (estudios abiertos únicamente). Filtrar esta lista de estudios según la ubicación, el estado del estudio y más. A Study to Identify Biomarkers in the Blood, Saliva or Tissue for Oropharyngeal Squamous Cell Cancer Rochester, Minn. The purpose of this study is to identify a biomarker (or biomarkers) that is present when disease is present (i.e., at diagnosis or recurrence) and not present when disease is absent (i.e., after treatment, in HPV negative patients or in normal controls). A Study to Evaluate Quality of Life Outcomes for Cholesteatoma Rochester, Minn. The purpose of this study is to determine the quality of life scores for patients that have undergone subtotal petrosectomy and ear canal closure for cholesteatoma and/or chronic otitis media utilizing two previously validated quality-of-life scales. Quality of Life in Patients with Acoustic Neuromas Rochester, Minn. Acoustic neuromas (also known as vestibular schwannomas) are benign slow growing tumors that arise from the vestibular portion of the eighth cranial nerve. Current treatment options include microsurgery, stereotactic radiosurgery and observation, using a “wait-and-scan” approach. The primary objective of this study is to compare long-term quality of life outcomes between treatments for sporadic acoustic neuromas. Vocal Disorders Co-existing in Patients with Spasmotic Dsyphonia (SD) Jacksonville, Fla. The purpose of this study is to investigate if SD patients have vocal disorders (nodules, polyps, muscle tension dysphonia etc) more than in normal population. BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study Jacksonville, Fla., Scottsdale/Phoenix, Ariz. The purpose of this study is to evaluate the feasibility of molecular characterization based on tumor mutational burden (TMB) for participant stratification, as assessed by the proportion of participants with less than or equal to a 21-day turnaround time for biopsy results in Stage I of the study. Also, to evaluate the feasibility of molecular characterization based on TMB and gene expression profiling (GEP) (for TIS - tumor inflammation signature) for stratification in the overall study (Stage I and Stage II). Additinoally, to evaluate the effectiveness by overall response rate (ORR – defined as confirmed and unconfirmed partial responses plus complete responses) of cabozantinib plus nivolumab in each disease cohort, both across and within tumor biomarker subgroups. A Study of the Biological System of Allergic Fungal Sinusitis Mucin Jacksonville, Fla. The purpose of this study is to describe the proteome of mucus in patients without chronic rhinosinusitis (nCRS) with an emphasis on cytokines and bone morphogenic proteins present (BMPs), to describe the proteome of mucus in patients with chronic rhinosinusitis without polyps (CRSsNP) with an emphasis on cytokines and BMPs present, to describe the proteome of mucus in patients with allergic fungal sinusitis (AFRS) with an emphasis on cytokines and BMPs present, and to identify BMPs differentially elevated in patients with AFRS compared to patients with nCRS or CRS. In-home Versus In-Clinic Subcutaneous Nivolumab Administration through Connected and Remote Cancer CARE Beyond Walls Jacksonville, Fla. The purpose of this study is to evaluate the impact of the location of SQ Nivo administration, at the infusion center or in the home, on patient preference and acceptability, safety, patient reported outcomes (PROs), and clinical outcomes. A Study to Develop a Biorepository of Blood Samples from Cancer Patients Participating in the Gemini (IRB 19-006717) Protocol Jacksonville, Fla., Scottsdale/Phoenix, Ariz. The purpose of this study is to develop a biorepository of blood samples from cancer patients participating in the Gemini (IRB 19-006717) protocol. These samples will be used for future biomarker discovery and other translational studies. Study of Treating Patients with Vestibular Schwannoma with Aspirin Rochester, Minn. The purpose of this study is to evaluate whether the administration of aspirin can delay or slow tumor growth and maintain or improve hearing in patients with vestibular schwannoma (VS). A Study to Evaluate Impedance Monitoring in Cochlear Implants Rochester, Minn. The purpose of this study is to determine changes in cochlear implant electrode impedances as a function over a period of time. Numeración de páginas Estudios clínicos AnteriorPágina anterior Ir a página 11 Ir a página 22 Ir a página 33 SiguientePróxima página A continuación se enumeran ensayos clínicos actuales.25 estudios en Otorrinolaringología (oído, nariz y garganta) y cirugía de cabeza y cuello (estudios abiertos únicamente). Filtrar esta lista de estudios según la ubicación, el estado del estudio y más. A Study to Identify Biomarkers in the Blood, Saliva or Tissue for Oropharyngeal Squamous Cell Cancer Rochester, Minn. The purpose of this study is to identify a biomarker (or biomarkers) that is present when disease is present (i.e., at diagnosis or recurrence) and not present when disease is absent (i.e., after treatment, in HPV negative patients or in normal controls). A Study to Evaluate Quality of Life Outcomes for Cholesteatoma Rochester, Minn. The purpose of this study is to determine the quality of life scores for patients that have undergone subtotal petrosectomy and ear canal closure for cholesteatoma and/or chronic otitis media utilizing two previously validated quality-of-life scales. Quality of Life in Patients with Acoustic Neuromas Rochester, Minn. Acoustic neuromas (also known as vestibular schwannomas) are benign slow growing tumors that arise from the vestibular portion of the eighth cranial nerve. Current treatment options include microsurgery, stereotactic radiosurgery and observation, using a “wait-and-scan” approach. The primary objective of this study is to compare long-term quality of life outcomes between treatments for sporadic acoustic neuromas. Vocal Disorders Co-existing in Patients with Spasmotic Dsyphonia (SD) Jacksonville, Fla. The purpose of this study is to investigate if SD patients have vocal disorders (nodules, polyps, muscle tension dysphonia etc) more than in normal population. BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study Jacksonville, Fla., Scottsdale/Phoenix, Ariz. The purpose of this study is to evaluate the feasibility of molecular characterization based on tumor mutational burden (TMB) for participant stratification, as assessed by the proportion of participants with less than or equal to a 21-day turnaround time for biopsy results in Stage I of the study. Also, to evaluate the feasibility of molecular characterization based on TMB and gene expression profiling (GEP) (for TIS - tumor inflammation signature) for stratification in the overall study (Stage I and Stage II). Additinoally, to evaluate the effectiveness by overall response rate (ORR – defined as confirmed and unconfirmed partial responses plus complete responses) of cabozantinib plus nivolumab in each disease cohort, both across and within tumor biomarker subgroups. A Study of the Biological System of Allergic Fungal Sinusitis Mucin Jacksonville, Fla. The purpose of this study is to describe the proteome of mucus in patients without chronic rhinosinusitis (nCRS) with an emphasis on cytokines and bone morphogenic proteins present (BMPs), to describe the proteome of mucus in patients with chronic rhinosinusitis without polyps (CRSsNP) with an emphasis on cytokines and BMPs present, to describe the proteome of mucus in patients with allergic fungal sinusitis (AFRS) with an emphasis on cytokines and BMPs present, and to identify BMPs differentially elevated in patients with AFRS compared to patients with nCRS or CRS. In-home Versus In-Clinic Subcutaneous Nivolumab Administration through Connected and Remote Cancer CARE Beyond Walls Jacksonville, Fla. The purpose of this study is to evaluate the impact of the location of SQ Nivo administration, at the infusion center or in the home, on patient preference and acceptability, safety, patient reported outcomes (PROs), and clinical outcomes. A Study to Develop a Biorepository of Blood Samples from Cancer Patients Participating in the Gemini (IRB 19-006717) Protocol Jacksonville, Fla., Scottsdale/Phoenix, Ariz. The purpose of this study is to develop a biorepository of blood samples from cancer patients participating in the Gemini (IRB 19-006717) protocol. These samples will be used for future biomarker discovery and other translational studies. Study of Treating Patients with Vestibular Schwannoma with Aspirin Rochester, Minn. The purpose of this study is to evaluate whether the administration of aspirin can delay or slow tumor growth and maintain or improve hearing in patients with vestibular schwannoma (VS). A Study to Evaluate Impedance Monitoring in Cochlear Implants Rochester, Minn. The purpose of this study is to determine changes in cochlear implant electrode impedances as a function over a period of time. Numeración de páginas Estudios clínicos AnteriorPágina anterior Ir a página 11 Ir a página 22 Ir a página 33 SiguientePróxima página Solicite una consulta Grupos especializadosInvestigación Jan. 28, 2025 Comparte en: FacebookTwitter Mostrar referencias Otorrinolaringología (oído, nariz y garganta) y cirugía de cabeza y cuelloSeccionesSolicita una consultaDescripción generalAnálisis y procedimientosEnfermedades tratadasMédicosMédicos por sede y especialidadGrupos especializadosEnsayos clínicosInvestigaciónCostos & seguro médicoRemisiones Investigación: los pacientes son la prioridad Mostrar la transcripción Para video Investigación: los pacientes son la prioridad [SUENA MÚSICA] Dr. Joseph Sirven, profesor de Neurología, Mayo Clinic: La misión de Mayo se centra en el paciente. La prioridad es el paciente. Aquí, la misión y la investigación se hacen para progresar en la forma de ayudar mejor al paciente y para asegurarnos de que el paciente sea la prioridad en la atención médica. De muchas maneras, esto equivale a un ciclo. Puede comenzar con algo tan simple como una idea que se desarrolla en un laboratorio, se traslada a la atención directa del paciente y, si todo sale bien y resulta útil o beneficioso, pasa a ser el método estándar. Creo que una de las características tan singulares de la forma de investigar en Mayo es la concentración en el paciente, y es lo que realmente le ayuda a captar la atención de todos. SeccionesSolicita una consultaDescripción generalAnálisis y procedimientosEnfermedades tratadasMédicosMédicos por sede y especialidadGrupos especializadosEnsayos clínicosInvestigaciónCostos & seguro médicoRemisiones ORG-20424058 Centros y departamentos médicos Otorrinolaringología (oído, nariz y garganta) y cirugía de cabeza y cuello