July 29, 2021
  1. AskMayoExpert. Antidepressant medications and pharmacogenomics. Minn.: Mayo Foundation for Medical Education and Research; 2017.
  2. Hall-Flavin DK, et al. Utility of integrated pharmacogenomic testing to support the treatment of major depressive disorder in a psychiatric outpatient setting. Pharmacogenetics and Genomics. 2013;23:535.
  3. Tantisira K, et al. Overview of pharmacogenomics. https://www.uptodate.com/contents/search. Accessed May 17, 2018.
  4. Dubovsky SL. The limits of genetic testing in psychiatry. Psychotherapy and Psychosomatics. 2016;85:129.
  5. Bousman CA, et al. Antidepressant prescribing in the precision medicine era: A prescriber's primer on pharmacogenetic tools. BMC Psychiatry. 2017;17:60.
  6. Fabbri C, et al. New insights on the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: Rare variant analysis and high-density imputation. The Pharmacogenomics Journal. 2018;18:413.
  7. Pharmacogenomics. National Institute of General Medical Sciences. https://www.nigms.nih.gov/education/pages/factsheet-pharmacogenomics.aspx. Accessed May 17, 2018.
  8. Altar CA, et al. Clinical validity: Combinatorial pharmacogenomics predicts antidepressant responses and healthcare utilizations better than single gene phenotypes. The Pharmacogenomics Journal. 2015;15:443.
  9. Perlis RH. Pharmacogenomic testing and personalized treatment of depression. Clinical Chemistry. 2014;60:53.
  10. Biemacka JM, et al. The International SSRI Pharmacogenomics Consortium (ISPC): A genome-wide association study of antidepressant treatment response. Translational Psychiatry. 2015;5:e533.
  11. Ahmed AT, et al. Benefits of and barriers to pharmacogenomics: Guided treatment for major depressive disorder. Clinical Pharmacology and Therapeutics. 2018;103:767.
  12. Cytochrome P450 2D6 (CYP2D6) Comprehensive Cascade. Mayo Medical Laboratories. https://www.mayomedicallaboratories.com/test-catalog/Specimen/97392. Accessed May 29, 2018.
  13. Cytochrome P450 2C19 Genotype. Mayo Medical Laboratories. https://www.mayomedicallaboratories.com/test-catalog/Overview/97390. Accessed May 29, 2018.
  14. Cytochrome P450 2C9 Genotype. Mayo Medical Laboratories. https://www.mayomedicallaboratories.com/test-catalog/Overview/97391. Accessed May 29, 2018.
  15. Hall-Flavin DK (expert opinion). Mayo Clinic, Rochester, Minn. June 27, 2018.
  16. Arwood MJ, et al. Implementing pharmacogenomics at your institution: Establishment and overcoming implementation challenges. Clinical and Translational Science. 2016;9:233.

Pruebas de citocromo P450 (CYP450)