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Part 2 of the study will prospectively evaluate the urine concentrations of mast cell mediators in a cohort of pediatric allergic disorder patients including ...
The investigators have chosen this population because 1) These mutations are the most common genetic causes of LQTS, and 2) Offspring will have high risk of ...
The second objective is to continue to identify whether there is a genetic link associated with MacTel Type 2. All participants who have not previously provided ...
The primary objective of the study is to compare sacituzumab tirumotecan combined with pembrolizumab to pembrolizumab alone with respect to overall survival ...
The objectives of this study are to determine the Maximum Tolerated Dose (MTD) and the Recommended Phase 2 Dose (RP2D) of NMS-03305293 in combination with ...
Descripción general. Diffuse large B-cell lymphoma (DLBCL) is a type of lymphoma. Lymphoma is cancer that affects the lymphatic system.
Patients in the GDC-0199+R arm will continue GDC-0199 treatment until disease progression or 2 years since treatment start, whichever comes first. Anticipated ...
All study subjects will receive acalabrutinib, durvalumab, and venetoclax. Acalabrutinib is FDA approved for treatment of chronic lymphocytic leukemia and small ...
... 2-6: 500 mg/m2). Patients randomized to B+R will receive 6 cycles of treatment consisting of a rituximab infusion (Cycle 1: 375 mg/m2; Cycles 2-6: 500 mg/m2) ...
In Part 2, the step-up dose identified in Part 1 will be used followed by the target dose of ABBV-383. Inotuzumab Ozogamicin and Post-Induction Chemotherapy in ...
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