Digestive Diseases

A continuación, se enumeran los ensayos clínicos actuales.

Filtra esta lista de estudios por sede, estado, etc.

1. Sponge and Eosinophil Peroxidase (EPO) Staining

   Rochester, Minn.

   Are we able to use the EPO staining technique using the sponge ?

2. Fecal Microbiome Transplant National Registry

   Rochester, Minn.

   The overarching goal of the FMT registry is to expand knowledge and optimize practice in the transplantation of fecal microbiota or other gut-related-microbiota products.

3. Whole Exome Sequencing and Other Emerging Technologies of Endoscopic Ultrasound Cytopathology

   Rochester, Minn.

   The purpose of this research study is to gather information on the feasibility of performing novel molecular analysis on Endoscopic Ultrasound acquired cytologic material and to assess molecular changes in cytology samples to see if that may aid treatment decision planning for future patients.

4. Cystic Kidney and Liver Disease Biobank

   Rochester, Minn.

    

   This research study is being done to create a collection of biospecimens (blood, urine, cyst fluid, bile, kidney or liver tissue, etc.) that can be used to facilitate the conduction of research on polycystic kidney and/or liver disease.

5. A Study Establishing a Registry for Endoscopic Suturing (ES)

   Jacksonville, Fla.

   The purpose of this study is to determine patient outcomes (survival, additional endoscopic or surgical procedures) with an endoscopic suturing technique at predetermined intervals compared to historical controls when applicable. To evaluate the effectiveness, safety, and durability of trans-orifice endoscopic suturing therapy for revision of bariatric procedures as well as study the safety, efficacy, and durability of preventative fixation of GI endoprosthetics.

6. Trial of Specific Carbohydrate and Mediterranean Diets to Induce Remission of Crohn's Disease

   Rochester, Minn.

   This protocol is designed to compare the effectiveness of two dietary interventions for patients with Crohn's disease (CD): the Specific Carbohydrate Diet (SCD) and a Mediterranean style diet (MSD) that has been demonstrated to have numerous other health benefits. The two diets will be compared in terms of their ability to resolve both the symptoms and bowel inflammation that characterize this debilitating disease.

7. A Study to Evaluate the Progression of Gastrointestinal and Fatigue Symptoms in the Scleroderma Population Seen at Mayo Clinic Arizona

   Scottsdale/Phoenix, Ariz.

   The purpose of this study is to evaluate the progression of gastrointestinal and fatigue symptoms over time (approximately 5 years) in the scleroderma population seen at Mayo Clinic Arizona.

8. A Study to Assess Gastric Functions

   Rochester, Minn.

   The purposes of this study are to assess gastric motility and emptying with scintigraphy in patients with upper gastrointestinal symptoms, to evaluate the relationship between daily symptoms and GE, motility, and symptoms during a GE study, to assess fasting and postprandial gastric volumes and motility with MRI in patients with upper gastrointestinal symptoms, and to compare gastric motility measured with scintigraphy and MRI.

    

9. REFINE: Regorafenib Observational Study in Hepatocellular Carcinoma

   Rochester, Minn.

   The purpose of this observational study is to describe the safety and effectiveness of regorafenib in patients with uHCC under real world practice conditions.

10. Tissue Collection for Patients with Cancers other than Hepatobilairy Cancers with Metastasis to the Liver

    Rochester, Minn.

    The goal of this study is to develop a resource (bank) of biospecimens (blood, tissue) from patients having cancers that metastasis to the liver. The purpose of the resource bank is to facilitate studies on the pathogenesis of cancers metastasizing to the liver and also in order to assess the ability of new tests to detect early cancer in the cohort of patients undergoing routine surveillance for cancer. The biospecimens will include cultures of tumor cells and tumor-associated non-malignant cells, as well as xenografts established from freshly isolated metastatic cancers in immunodeficient mice. We plan to administer a risk factor questionnaire to facilitate identification of risk factors for development of metastatic liver cancer. The study will also  determine survival of patients from time of diagnosis.