Proper Use

Drug information provided by: Merative, Micromedex®

Use this medicine exactly as directed by your doctor. Do not take more or less of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

You may take this medicine with or without food.

Swallow the extended-release tablet whole with water. Do not cut, crush, break, or chew it.

A part of the extended-release tablet may pass into your stools. This is normal and is nothing to worry about.

If you are taking the tablet form of this medicine, your doctor may switch you to the extended-release tablet form after your last dose. Ask your doctor if you have questions.

Measure the oral liquid medicine with an oral dosing syringe.

Use only the brand of medicine your doctor prescribed. Other brands may not work the same way.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For psoriatic arthritis, rheumatoid arthritis, and ankylosing spondylitis:
    • For oral dosage form (extended-release tablets):
      • Adults—11 milligrams (mg) once a day together with another medicine. Your doctor may adjust your dose as needed.
      • Children—Use and dose must be determined by your doctor.
    • For oral dosage form (tablets):
      • Adults—5 milligrams (mg) 2 times a day together with another medicine. Your doctor may adjust your dose as needed.
      • Children—Use and dose must be determined by your doctor.
  • For ulcerative colitis:
    • For oral dosage form (extended-release tablets):
      • Adults—22 milligrams (mg) once a day for at least 8 weeks, then 11 mg once a day. Your doctor may adjust your dose as needed.
      • Children—Use and dose must be determined by your doctor.
    • For oral dosage form (tablets):
      • Adults—10 milligrams (mg) 2 times a day for at least 8 weeks, then 5 or 10 mg 2 times a day. Your doctor may adjust your dose as needed.
      • Children—Use and dose must be determined by your doctor.
  • For pcJIA:
    • For oral dosage form (tablets):
      • Children 2 to 17 years of age—Dose is based on body weight and must be determined by your doctor.
        • Weighing 40 kilograms (kg) or more—5 milligrams (mg) 2 times a day. Your doctor may adjust your dose as needed.
        • Weighing 20 to less than 40 kg—4 mg 2 times a day. Your doctor may adjust your dose as needed.
        • Weighing 10 to less than 20 kg—3.2 mg 2 times a day. Your doctor may adjust your dose as needed.
      • Children younger than 2 years of age—Use and dose must be determined by your doctor.
    • For oral dosage form (solution):
      • Children 2 to 17 years of age—Dose is based on body weight and must be determined by your doctor.
        • Weighing 40 kilograms (kg) or more—5 milliliters (mL) 2 times a day. Your doctor may adjust your dose as needed.
        • Weighing 20 to less than 40 kg—4 mL 2 times a day. Your doctor may adjust your dose as needed.
        • Weighing 10 to less than 20 kg—3.2 mL 2 times a day. Your doctor may adjust your dose as needed.
      • Children younger than 2 years of age—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Use the oral liquid within 60 days of opening the bottle. Throw away any remaining oral liquid after 60 days.

Portions of this document last updated: April 01, 2024

Copyright: © Merative US L.P. 1973, 2024. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.