Side Effects

Información sobre medicamentos proporcionada por: IBM Micromedex

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Bleeding gums
  2. bloating or swelling of the face, arms, hands, fingers, lower legs, or feet
  3. blurred vision
  4. chest pain
  5. chills
  6. confusion
  7. coughing up blood
  8. cracked lips
  9. decreased urine output and frequency
  10. diarrhea
  11. difficulty with breathing or swallowing
  12. dilated neck veins
  13. dizziness
  14. dry mouth
  15. extreme tiredness or weakness
  16. fainting
  17. fast, slow, or irregular heartbeat
  18. fever
  19. headache
  20. increased menstrual flow or vaginal bleeding
  21. irregular breathing
  22. labored breathing
  23. lightheadedness
  24. nervousness
  25. nosebleeds
  26. paralysis
  27. pounding in the ears
  28. prolonged bleeding from cuts
  29. rapid breathing
  30. rapid weight gain
  31. red or black, tarry stools
  32. red or dark brown urine
  33. sores, ulcers, or white spots on the lips, tongue, or inside the mouth
  34. sunken eyes
  35. swelling or inflammation of the mouth
  36. thirst
  37. tightness in the chest
  38. tingling of the hands or feet
  39. troubled breathing
  40. unusual tiredness or weakness
  41. unusual weight gain or loss
  42. wrinkled skin
  43. yellow eyes or skin

Less common

  1. Bleeding from the rectum
  2. bleeding from wounds
  3. constipation
  4. depressed mood
  5. dry skin and hair
  6. feeling cold
  7. hair loss
  8. hoarseness or husky voice
  9. indigestion
  10. loss of appetite
  11. muscle cramps and stiffness
  12. nausea
  13. pain in the chest, groin, or legs, especially the calves
  14. pain in the stomach, side, or abdomen, possibly radiating to the back
  15. severe stomach pain
  16. severe, sudden headache
  17. slurred speech
  18. sudden loss of coordination
  19. sudden, severe weakness or numbness in the arm or leg
  20. vision changes
  21. vomiting
  22. vomiting of blood or material that looks like coffee grounds


  1. Back pain
  2. chest discomfort
  3. cloudy or bloody urine
  4. darkening of the skin
  5. drowsiness
  6. general feeling of tiredness or weakness
  7. irregular or slow heart rate
  8. light-colored stools
  9. mental depression
  10. seizures
  11. skin rash
  12. stomach pain, continuing

Incidence not known

  1. Blistering, peeling, or loosening of the skin
  2. cough
  3. dark-colored urine
  4. heavy feeling of the jaw
  5. increased thirst
  6. itching
  7. joint pain, stiffness, or swelling
  8. loosening of a tooth
  9. lower back or side pain
  10. muscle cramps or spasms
  11. muscular pain, tenderness, wasting, or weakness
  12. pain, swelling, or numbness in the mouth or jaw
  13. painful or difficult urination
  14. pale skin
  15. red skin lesions, often with a purple center
  16. sore throat
  17. sudden, severe chest pain
  18. unusual bleeding or bruising
  19. weight gain

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Belching
  2. blistering, peeling, redness, or swelling of the palms, hands, or bottoms of the feet
  3. change in color of the treated skin
  4. change in taste
  5. difficulty with moving
  6. discouragement
  7. excess air or gas in the stomach or bowels
  8. feeling of fullness
  9. feeling sad or empty
  10. hair color changes
  11. hair loss or thinning of the hair
  12. heartburn
  13. irritability
  14. lack of appetite
  15. lack or loss of strength
  16. loss of interest or pleasure
  17. muscle aches or pains
  18. numbness, pain, tingling, or unusual sensations in the palms of the hands or bottoms of the feet
  19. pain or burning in the throat
  20. passing gas
  21. stomach discomfort, upset, or pain
  22. swollen joints
  23. trouble concentrating
  24. trouble sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.