Before Using

Información sobre medicamentos proporcionada por: IBM Micromedex

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of sodium nitroprusside injection in children.


No information is available on the relationship of age to the effects of sodium nitroprusside injection in geriatric patients. However, elderly patients are more likely to have low blood pressure, which may require caution in patients receiving this medicine.


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Sildenafil

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Anemia or
  • Hypovolemia (low blood volume)—Should be corrected first before using this medicine.
  • Anuria (trouble urinating) or
  • Liver disease—Use with caution. May increase risk for cyanide toxicity.
  • Circulation problems or
  • Heart disease (eg, arteriovenous shunting, coarctation of the aorta) or
  • Heart failure, acute caused by reduced peripheral vascular resistance or
  • Leber's optic atrophy, congenital or
  • Tobacco amblyopia—Should not be used in patients with these conditions.
  • Head injury or
  • Methemoglobinemia—Use with caution. May make these conditions worse.