Promethazine And Codeine (Oral Route)

Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

1. Bluish lips or skin
2. chills
3. clay-colored stools
4. cold sweats
5. confusion
6. cough
7. dark urine
8. decrease in the frequency of urination
9. decrease in the urine volume
10. diarrhea
11. difficult or troubled breathing
12. difficulty in passing urine (dribbling)
13. dizziness
14. dizziness, faintness, or lightheadedness when getting up from lying or sitting position
15. fast, pounding, or irregular heartbeat or pulse
16. feeling of warmth
17. fever
18. headache
19. high fever
20. hives or welts, itching, or rash
21. increased sweating
22. irregular, fast or slow, or shallow breathing
23. large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
24. loss of appetite
25. loss of bladder control
26. nausea
27. noisy breathing
28. not breathing
29. painful urination
30. pale or blue lips, fingernails, or skin
31. rectal bleeding
32. redness of the face, neck, arms, and occasionally, upper chest
33. redness of the skin
34. seeing, hearing, or feeling things that are not there
35. seizures
36. severe muscle stiffness
37. shakiness in the legs, arms, or hands
38. stomach pain
39. sweating
40. tightness in the chest
41. tiredness
42. trembling or shaking of the hands or feet
43. unpleasant breath odor
44. unusual tiredness or weakness
45. unusually pale skin
46. vomiting of blood
47. yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

1. Cold, clammy skin
2. dry mouth
3. fainting
4. no blood pressure or pulse
5. no muscle tone or movement
6. pinpoint pupils (black part of the eye)
7. stopping of the heart
8. unconsciousness

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

1. Bad dreams
2. blurred or loss of vision
3. confusion as to time, place, or person
4. continuing ringing or buzzing or other unexplained noise in the ears
5. difficulty having a bowel movement
6. disturbed color perception
7. double vision
8. drowsiness
9. false or unusual sense of well-being
10. halos around lights
11. hearing loss
12. holding false beliefs that cannot be changed by fact
13. increased sensitivity of the skin to sunlight
14. night blindness
15. overbright appearance of lights
16. redness or other discoloration of the skin
17. relaxed and calm feeling
18. severe sunburn
19. sleepiness
20. trouble sleeping
21. tunnel vision
22. unusual excitement, nervousness, or restlessness
23. vomiting

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

• Precautions

Portions of this document last updated: April 01, 2024

Copyright: © Merative US L.P. 1973, 2024. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.