Proper Use

Drug information provided by: Merative, Micromedex®

Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

The medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.

Take this medicine at the same time each day, with or without food.

Swallow the capsule whole with a cup of water. Do not open, crush, break, or chew it.

Be careful not to handle crushed or broken capsules. If you have contact with broken or crushed capsules, wash your skin with soap and clear water. If the medicine gets into your eyes, rinse them with water.

Avoid eating grapefruit, star fruit, or pomegranate and drinking grapefruit or pomegranate juice while using this medicine.

If you vomit after taking a dose, do not take another capsule. Wait and take your next dose at your usual time.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (capsules):
    • For multiple myeloma in combination with bortezomib and dexamethasone
      • Adults—At first, 20 milligrams (mg) once every other day for 3 doses per week (on Days 1, 3, 5, 8, 10, and 12) of weeks 1 and 2 of each 21-day cycle for 8 cycles. Your doctor may want you to continue treatment for an additional 8 cycles for a total of 16 cycles (48 weeks).
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Do not take this medicine if it has been more than 12 hours since you missed your last dose.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Store blister pack in the original carton to protect from light.

Portions of this document last updated: March 01, 2024

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