Proper Use

Información sobre medicamentos proporcionada por: IBM Micromedex

A nurse or other trained health professional will give you or your child this medicine in a medical facility. It is given as a shot under your skin, usually in the upper arms, stomach, or thighs.

This medicine comes with a Medication Guide and patient instructions. Read and follow these instructions carefully. Ask your doctor or pharmacist if you have any questions.

If you are receiving this medicine for asthma or nasal polyps, you will receive omalizumab once every 2 or 4 weeks. Your dose will be determined by your IgE level, which your doctor will measure with a simple blood test before treatment begins, and your body weight. Based on your dose, your doctor will also tell you if you will need 1, 2, or 3 injections per dose. If you need more than 1 injection, each will be given in a different place on your body.

Omalizumab is not a rescue medication and should not be used to treat sudden asthma attacks. It is not a substitute for the medicines you are already taking. Never suddenly stop taking, or change the dose of your steroid medicine (inhaled or taken by mouth) unless your doctor tells you to do so.

If you are receiving this medicine for chronic idiopathic urticaria, you will receive this medicine every 4 weeks.

Omalizumab injection may also be given at home to patients who have received at least 3 doses of this medicine under the supervision of a doctor. If you are using this medicine at home, your doctor or nurse will teach you how to inject the medicine. Be sure that you understand exactly how to use this.

If you use this medicine at home, you will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas. This will help prevent skin problems. Do not inject into scars, moles, or skin areas that are red, bruised, tender, hard, or not intact.

Allow the prefilled syringe to warm to room temperature for 15 to 30 minutes before using it. Do not warm the medicine in any other way.

Check the liquid in the prefilled syringe. It should be clear and colorless to pale brownish yellow. Do not use this medicine if it is cloudy, discolored, or if you see particles in it.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For injection dosage form (prefilled syringe):
    • For asthma:
      • Adults and children 12 years of age and older—Dose is based on IgE level and body weight, and must be determined by your doctor. The dose is usually 150 to 375 milligrams (mg) injected under your skin every 2 or 4 weeks. Your doctor may adjust your dose as needed and tolerated.
      • Children 6 to younger than 12 years of age—Dose is based on IgE level and body weight, and must be determined by your doctor. The dose is usually 75 to 375 mg injected under your skin every 2 or 4 weeks. Your doctor may adjust your dose as needed and tolerated.
      • Children younger than 6 years of age—Use and dose must be determined by your doctor.
    • For nasal polyps:
      • Adults—Dose is based on IgE level and body weight, and must be determined by your doctor. The dose is usually 75 to 600 milligrams (mg) injected under your skin every 2 or 4 weeks. Your doctor may adjust your dose as needed and tolerated.
      • Children—Use and dose must be determined by your doctor.
    • For chronic idiopathic urticaria:
      • Adults and children 12 years of age and older—150 or 300 milligrams (mg) injected under your skin every 4 weeks. Your doctor may adjust your dose as needed and tolerated.
      • Children younger than 12 years of age—Use and dose must be determined by your doctor.

Missed Dose

This medicine needs to be given on a fixed schedule. If you miss a dose or forget to use your medicine, call your doctor or pharmacist for instructions.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store in the refrigerator. Do not freeze.

Protect the medicine from direct light. Keep the medicine in the original carton until you are ready to use it. Throw away any unused medicine after 4 hours of removing from the refrigerator. Do not use if the prefilled syringe has been frozen.

Throw away used prefilled syringes in a sharps disposal container or in a hard, closed container where the needles cannot poke through. Keep this container away from children and pets.