Proper Use

Información sobre medicamentos proporcionada por: IBM Micromedex

Medicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

This medicine should come with a patient information leaflet. It is very important that you read and understand this information. Be sure to ask your doctor about anything you do not understand.

This medicine should be taken once a week on the same day and at the same time, especially for the first 3 weeks. Take it at least 1 hour before or at least 2 hours after food.

Swallow the capsule whole with water. Do not open, crush, or chew it.

Be careful not to handle crushed or broken capsules. If you have contact with broken or crushed capsules, wash your skin with soap and water. If the medicine gets into your eyes, rinse them with water.


The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (capsules):
    • For multiple myeloma (in combination with lenalidomide and dexamethasone):
      • Adults—At first, 4 milligrams (mg) once a week, taken on Days 1, 8, and 15 of a 28-day cycle. Your doctor may adjust your dose as needed.
      • Children—Use and dose must be determined by your doctor.

Missed Dose

If you vomit after taking your medicine, call your doctor or pharmacist for instructions.

If you miss a dose or forget to use your medicine, take it if your next regular dose is more than 72 hours away. If your next dose is within 72 hours, wait until then to use the medicine and skip the missed dose. If you vomit after taking a dose, do not repeat the dose. Take your next dose at the regular schedule.


Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep your medicine in the original package until you are ready to use it.