Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  1. Anxiety
  2. bleeding, hard lump, hives or welts, itching, pain, redness, or swelling at the injection site
  3. chest pain
  4. cough or hoarseness
  5. excessive muscle tone
  6. fast, irregular, pounding, or racing heartbeat or pulse
  7. feeling of warmth
  8. fever or chills
  9. joint pain
  10. lower back or side pain
  11. neck pain
  12. painful or difficult urination
  13. redness of the face, neck, arms, and occasionally, upper chest
  14. skin rash
  15. swelling or puffiness of the face
  16. swollen, painful, or tender lymph glands in the neck, armpit, or groin
  17. troubled breathing

Less common

  1. Agitation
  2. bloating or swelling
  3. confusion
  4. difficulty with swallowing
  5. feeling faint, dizzy, or lightheaded
  6. headache, severe and throbbing
  7. itching of the vagina or outside genitals
  8. muscle aches
  9. pain
  10. pain during sexual intercourse
  11. purple spots under the skin
  12. rapid weight gain
  13. red streaks on the skin
  14. shakiness in the legs, arms, hands, or feet
  15. small lumps under the skin
  16. spasm of the throat
  17. strong urge to urinate
  18. sweating
  19. swelling of the fingers, arms, feet, or legs
  20. thick, white curd-like vaginal discharge without odor or with mild odor
  21. tightness in the chest
  22. tingling of the hands or feet
  23. trembling or shaking of the hands or feet
  24. unusual weight gain or loss


  1. Blood in the urine
  2. burning or stinging of the skin
  3. continuous, uncontrolled back-and-forth or rolling eye movements
  4. decreased sexual ability
  5. diarrhea
  6. difficulty with moving
  7. ear pain
  8. fast breathing
  9. irritation of the mouth and tongue (thrush)
  10. loss of appetite
  11. menstrual pain or changes
  12. painful cold sores or blisters on the lips, nose, eyes, or genitals
  13. sensation of motion, usually whirling, either of oneself or of one's surroundings
  14. speech problems
  15. vision problems

Incidence not known

  1. Abnormal vaginal bleeding or discharge
  2. back pain, sudden and severe
  3. bleeding gums
  4. blindness
  5. blurred vision
  6. chest discomfort or heaviness
  7. clear or bloody discharge from the nipple
  8. cloudy urine
  9. coughing up blood
  10. dark urine
  11. decreased urine output
  12. decreased vision
  13. difficult or frequent urination
  14. dilated neck veins
  15. dimpling of the breast skin
  16. drowsiness
  17. extreme tiredness or weakness
  18. eye pain
  19. gaseous abdominal or stomach pain
  20. general feeling of discomfort or illness
  21. general tiredness and weakness
  22. hair loss
  23. headache
  24. increased menstrual flow or vaginal bleeding
  25. inverted nipple
  26. joint swelling
  27. large amount of cholesterol in the blood
  28. light-colored stools
  29. lump in the breast or under the arm
  30. lump or swelling in the stomach
  31. muscle weakness, sudden and progressing
  32. nausea
  33. nosebleed
  34. pain or discomfort the in arms or jaw
  35. paralysis
  36. persistent crusting or scaling of the nipple
  37. prolonged bleeding from cuts
  38. puffiness or swelling of the eyelids or around the eyes, lips, or tongue
  39. rapid, shallow breathing
  40. recurrent fever
  41. red or black, tarry stools
  42. redness or swelling of the breast
  43. seizures
  44. severe headache
  45. sore on the skin of the breast that does not heal
  46. sore throat
  47. stiff neck or back
  48. stomach bloating, burning, cramping, or pain
  49. tearing
  50. tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over the affected area
  51. unusual tiredness or weakness
  52. upper right abdominal or stomach pain
  53. vomiting
  54. yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Lack or loss of strength
  2. stuffy or runny nose

Less common

  1. Double vision

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.