Esomeprazole (Oral Route)

Side Effects

Drug information provided by: Merative, Micromedex®

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

1. Black, tarry stools
2. blistering, peeling, or loosening of the skin
3. bloating
4. chest pain or tightness
5. chills
6. confusion
7. constipation
8. cough
9. darkened urine
10. decreased urine
11. difficulty with swallowing
12. dizziness
13. drowsiness
14. dry mouth
15. fast heartbeat
16. fever
17. indigestion
18. joint or muscle pain
19. loss of appetite
20. mood or mental changes
21. muscle cramps in the hands, arms, feet, legs, or face
22. muscle spasms (tetany) or twitching
23. nausea
24. numbness and tingling around the mouth, fingertips, or feet
25. painful or difficult urination
26. pains in the stomach, side, or abdomen, possibly radiating to the back
27. puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
28. red skin lesions, often with a purple center
29. red, irritated eyes
30. seizures
31. skin rash, hives, itching
32. sore throat
33. sores, ulcers, or white spots in the mouth or on the lips
34. stomach cramps
35. swollen glands
36. trouble breathing
37. trembling
38. unusual bleeding or bruising
39. unusual tiredness or weakness
40. vomiting
41. yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

1. Bad, unusual, or unpleasant (after) taste
2. change in taste

Less common

1. Sleepiness or unusual drowsiness

Rare

1. Acne
2. back pain

Incidence not known

1. Agitation
2. decreased interest in sexual intercourse
3. excess air or gas in the stomach or bowels
4. full feeling
5. inability to have or keep an erection
6. increased sensitivity of the skin to sunlight
7. loss in sexual ability, desire, drive, or performance
8. loss or thinning of the hair
9. muscular weakness
10. passing gas
11. redness or other discoloration of the skin
12. seeing, hearing, or feeling things that are not there
13. severe sunburn
14. swelling of the breasts or breast soreness in both females and males
15. swelling or inflammation of the mouth
16. swollen joints

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

• Precautions

Portions of this document last updated: March 01, 2024

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