Precautions
Drug information provided by: Merative, Micromedex®
It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. Blood tests may be needed to check for unwanted effects.
Do not use this medicine together with dimethyl fumarate (Tecfidera®). Using these medicines together may cause serious side effects.
This medicine may cause serious allergic reactions, including anaphylaxis and angioedema, which can be life-threatening and require immediate medical attention. Call your doctor right away if you have a rash, itching, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth while you are using this medicine.
This medicine can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection (including herpes). Avoid being near people who are sick or have infections while you are using this medicine. Wash your hands often. Tell your doctor if you have any kind of infection before you start using this medicine. Also tell your doctor if you have ever had an infection that would not go away or an infection that kept coming back.
Check with your doctor right away if you think you are getting an infection or if you get a fever, chills, cough, hoarseness, lower back or side pain, painful or difficult urination, burning or stinging of the skin, painful cold sores or blisters on the lips, nose, eyes, genitals, or trunk of body, chest pain, coughing or spitting up blood, sore throat, muscle aches, night sweats, trouble breathing, or unusual tiredness.
This medicine may increase your risk of developing a serious and rare brain infection called progressive multifocal leukoencephalopathy (PML). Check with your doctor right away if you have vision changes, loss of coordination, clumsiness, memory loss, difficulty speaking or understanding what others say, or weak legs.
Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, vomiting, or yellow eyes or skin. These could be symptoms of a serious liver problem.
This medicine may cause skin flushing. Tell your doctor right away if you have warmth, redness, itching, or a burning sensation in your face, neck, arms, or upper chest while using this medicine.
Do not drink alcohol while you are using this medicine.
Make sure your doctor know if you are pregnant or planning to become pregnant before using this medicine.
This medicine may cause serious stomach or bowel problems (eg, bleeding, blockage, perforation, or ulcers). Check with your doctor right away if you have black, tarry stools, constipation, diarrhea, fever, heartburn, indigestion, nausea, stomach pain, cramps, or burns, or vomiting of blood or material that looks like coffee grounds.
Portions of this document last updated: Feb. 01, 2024
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