Before Using

Información sobre medicamentos proporcionada por: IBM Micromedex

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of desmopressin nasal spray to treat central diabetes insipidus in children 3 months of age and older for desmopressin acetate or in children 4 years of age and older for DDAVP®. Safety and efficacy have been established.

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of Stimate® to treat hemophilia A and von Willebrand disease in children 11 months of age and older. However, use is not recommended in children younger than 11 months of age.

Appropriate studies have not been performed on the relationship of age to the effects of Noctiva™ in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of desmopressin nasal spray in the elderly. However, elderly patients are more likely to have age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving desmopressin.

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of Noctiva™ in the elderly. However, elderly patients are more likely to have hyponatremia (low sodium in the blood), which may require caution and an adjustment in the dose for patients receiving Noctiva™.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Alclometasone
  • Aldosterone
  • Amcinonide
  • Beclomethasone
  • Betamethasone
  • Budesonide
  • Bumetanide
  • Ciclesonide
  • Clobetasol
  • Clobetasone
  • Clocortolone
  • Cortisone
  • Deflazacort
  • Desonide
  • Desoximetasone
  • Dexamethasone
  • Diflorasone
  • Diflucortolone
  • Difluprednate
  • Ethacrynic Acid
  • Flucloronide
  • Fludrocortisone
  • Flumethasone
  • Flunisolide
  • Fluocinolone
  • Fluocinonide
  • Fluocortin
  • Fluocortolone
  • Fluorometholone
  • Flurandrenolide
  • Fluticasone
  • Furosemide
  • Halcinonide
  • Halobetasol
  • Hydrocortisone
  • Loteprednol
  • Medrysone
  • Methylprednisolone
  • Mometasone
  • Paramethasone
  • Prednicarbate
  • Prednisolone
  • Prednisone
  • Rimexolone
  • Torsemide
  • Triamcinolone

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Aceclofenac
  • Acemetacin
  • Acetohexamide
  • Alfentanil
  • Amineptine
  • Amitriptyline
  • Amitriptylinoxide
  • Amoxapine
  • Amtolmetin Guacil
  • Anileridine
  • Aspirin
  • Bendroflumethiazide
  • Benzhydrocodone
  • Benzthiazide
  • Bromfenac
  • Bufexamac
  • Buprenorphine
  • Butorphanol
  • Carbamazepine
  • Celecoxib
  • Chlorothiazide
  • Chlorpromazine
  • Chlorpropamide
  • Chlorthalidone
  • Choline Salicylate
  • Citalopram
  • Clomipramine
  • Clonixin
  • Clopamide
  • Codeine
  • Desipramine
  • Dexibuprofen
  • Dexketoprofen
  • Dezocine
  • Diacetylmorphine
  • Diazoxide
  • Dibenzepin
  • Diclofenac
  • Difenoxin
  • Diflunisal
  • Dihydrocodeine
  • Diphenoxylate
  • Dipyrone
  • Doxepin
  • Droxicam
  • Escitalopram
  • Ethylmorphine
  • Etodolac
  • Etofenamate
  • Etoricoxib
  • Felbinac
  • Fenoprofen
  • Fentanyl
  • Fepradinol
  • Feprazone
  • Floctafenine
  • Flufenamic Acid
  • Fluoxetine
  • Flurbiprofen
  • Fluvoxamine
  • Gliclazide
  • Glimepiride
  • Glipizide
  • Gliquidone
  • Glyburide
  • Hydrochlorothiazide
  • Hydrocodone
  • Hydroflumethiazide
  • Hydromorphone
  • Ibuprofen
  • Imipramine
  • Indapamide
  • Indomethacin
  • Ketobemidone
  • Ketoprofen
  • Ketorolac
  • Lamotrigine
  • Levorphanol
  • Lofepramine
  • Lornoxicam
  • Loxoprofen
  • Lumiracoxib
  • Meclofenamate
  • Mefenamic Acid
  • Melitracen
  • Meloxicam
  • Meperidine
  • Meptazinol
  • Methadone
  • Methyclothiazide
  • Metolazone
  • Morniflumate
  • Morphine
  • Morphine Sulfate Liposome
  • Nabumetone
  • Nalbuphine
  • Naproxen
  • Nepafenac
  • Nicomorphine
  • Niflumic Acid
  • Nimesulide
  • Nimesulide Beta Cyclodextrin
  • Nortriptyline
  • Opipramol
  • Opium
  • Opium Alkaloids
  • Oxaprozin
  • Oxycodone
  • Oxymorphone
  • Oxyphenbutazone
  • Papaveretum
  • Parecoxib
  • Paregoric
  • Paroxetine
  • Pentazocine
  • Phenylbutazone
  • Piketoprofen
  • Piritramide
  • Piroxicam
  • Polythiazide
  • Pranoprofen
  • Proglumetacin
  • Propyphenazone
  • Proquazone
  • Protriptyline
  • Remifentanil
  • Rofecoxib
  • Salicylic Acid
  • Salsalate
  • Sertraline
  • Sodium Salicylate
  • Sufentanil
  • Sulindac
  • Tapentadol
  • Tenoxicam
  • Tianeptine
  • Tiaprofenic Acid
  • Tilidine
  • Tolazamide
  • Tolbutamide
  • Tolfenamic Acid
  • Tolmetin
  • Tolvaptan
  • Tramadol
  • Trichlormethiazide
  • Trimipramine
  • Valdecoxib
  • Vilazodone
  • Vortioxetine
  • Xipamide

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Blood clotting problems or
  • Hypertension (high blood pressure) or
  • Hypotension (low blood pressure) or
  • Tachycardia (increased heart rate)—Use with caution. May make these conditions worse.
  • Coronary artery disease or
  • Cystic fibrosis or
  • Heart failure or
  • Kidney problems or
  • Polydipsia (excessive thirst), habitual or psychogenic—Use with caution. May cause side effects to become worse.
  • Congestive heart failure or
  • Head injury or
  • Hypertension (high blood pressure), uncontrolled or
  • Urinary retention, or history of—Noctiva™ can cause fluid retention, and should not be used in patients with these conditions.
  • Gastroenteritis or
  • Infection (systemic) or
  • Polydipsia (excessive thirst) or
  • Primary nocturnal enuresis (bed-wetting at night) or
  • Salt-wasting nephropathies or
  • Syndrome of inappropriate antidiuretic hormone (SIADH), known or suspected—Noctiva™ should not be used in patients with these conditions.
  • Hyponatremia (low sodium in the blood), or history of or
  • Kidney disease, moderate to severe—Should not be used in patients with these conditions.
  • Nose problems (eg, blockage, nasal mucosa atrophy, rhinitis) or
  • Nose surgery (eg, transsphenoidal hypophysectomy)—Use with caution. May increase risk for more serious side effects.
  • Type IIB von Willebrand disease—Stimate® should not be used in patients with this condition.