Proper Use

Drug information provided by: Merative, Micromedex®

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

The tablets should be taken with meals to help reduce unwanted stomach effects that may occur during the first few weeks.

Swallow the extended-release tablet whole. Do not crush, break, or chew it. It should be taken with the morning meal.

A part of the extended-release tablet may pass into your stool. This is normal and is nothing to worry about.

Tell your doctor if you are on a low-salt or sodium diet.

If you are taking an evening dose of metformin extended-release tablets, you should skip the last dose before starting treatment with this medicine the following morning.

Carefully follow the special meal plan your doctor gave you. This is the most important part of controlling your diabetes, and will help the medicine work properly. Exercise regularly and test for sugar in your blood or urine as directed.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For type 2 diabetes:
    • For oral dosage form (extended-release tablets):
      • For patients not on canagliflozin or metformin treatment:
        • Adults—2 tablets once a day. Each tablet contains canagliflozin 50 milligrams (mg) and metformin 500 mg. Your doctor may adjust your dose as needed.
        • Children—Use and dose must be determined by your doctor.
      • For patients on metformin treatment:
        • Adults—2 tablets once a day. This is equivalent to canagliflozin 100 milligrams (mg) plus the total daily dose of metformin already being taken. Your doctor may adjust your dose as needed. However, the dose is usually not more than metformin 2000 mg and canagliflozin 300 mg per day.
        • Children—Use and dose must be determined by your doctor.
      • For patients on canagliflozin treatment:
        • Adults—2 tablets once a day. This is equivalent to metformin 1000 milligrams (mg) plus the total daily dose of canagliflozin already being taken. Your doctor may adjust your dose as needed. However, the dose is usually not more than metformin 2000 mg and canagliflozin 300 mg per day.
        • Children—Use and dose must be determined by your doctor.
      • For patients previously treated with canagliflozin and metformin:
        • Adults—2 tablets once a day. The total daily dose is the same as the dose you are already taking. Your doctor may adjust your dose as needed. However, the dose is usually not more than metformin 2000 mg and canagliflozin 300 mg per day.
        • Children—Use and dose must be determined by your doctor.
    • For oral dosage form (tablets):
      • For patients not on canagliflozin or metformin treatment:
        • Adults—One tablet 2 times a day. Each tablet contains canagliflozin 50 milligrams (mg) and metformin 500 mg. Your doctor may adjust your dose as needed.
        • Children—Use and dose must be determined by your doctor.
      • For patients on metformin treatment:
        • Adults—One tablet 2 times a day. This is equivalent to canagliflozin 100 milligrams (mg) plus the daily dose of metformin already being taken, divided into two doses. Your doctor may adjust your dose as needed. However, the dose is usually not more than metformin 2000 mg and canagliflozin 300 mg per day.
        • Children—Use and dose must be determined by your doctor.
      • For patients on canagliflozin treatment:
        • Adults—One tablet 2 times a day. This is equivalent to metformin 1000 milligrams (mg) plus the total daily dose of canagliflozin already being taken, divided into two doses. Your doctor may adjust your dose as needed. However, the dose is usually not more than metformin 2000 mg and canagliflozin 300 mg per day.
        • Children—Use and dose must be determined by your doctor.
      • For patients previously treated with canagliflozin and metformin:
        • Adults—One tablet 2 times a day. The total daily dose is the same as the dose you are already taking. Your doctor may adjust your dose as needed. However, the dose is usually not more than metformin 2000 mg and canagliflozin 300 mg per day.
        • Children—Use and dose must be determined by your doctor.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep the tablets in its original container to protect them from moisture. You may also store the tablets in a pill box or pill organizer for up to 30 days only.

Portions of this document last updated: April 01, 2024

Copyright: © Merative US L.P. 1973, 2024. All rights reserved. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.