Stem cell donors sought for Best disease clinical trial
Recent studies of the mechanisms underlying the bestrophinopathies indicate that four degenerative retinal diseases are associated with disparate effects on bestrophin-1 localization, but not oligomerization. Stem cell donors are needed for further research into a cure for Best disease.
Increases in antidepressant use may contribute to growth of incident cataract
A retrospective, population-based study indicates that cataract surgery in people age 50 years or older was significantly associated with an increased use of selective serotonin reuptake inhibitors, the most commonly prescribed antidepressants in the U.S.
FECD is likely a trinucleotide repeat expansion
Researchers at Mayo Clinic have identified the specific genetic defect in the TCF4 gene — the expansion of the TGC repeat — that appears to be responsible for Fuchs' endothelial corneal dystrophy (FECD).
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