Ensayos clínicos A continuación, se enumeran los ensayos clínicos actuales.18 estudios en Oftalmología (solo estudios abiertos). Filtra esta lista de estudios por sede, estatus, etc. A Study to Evaluate Advanced Ultrasound Techniques for Diagnosis of Giant Cell Arteritis Rochester, Minn. The purpose of this study is to find out if advanced ultrasound studies can be used to make a diagnosis of giant cell arteritis. Ultimately, we hope to be able to offer non-invasive diagnostic options as an alternative to biopsy to future patients who are being evaluated for giant cell arteritis. A Study to Evaluate Patient Reported Outcome Measures in Children with Eye Conditions Rochester, Minn. The objectives of this study are: To evaluate patient-reported quality of life and functional vision across the spectrum of pediatric eye conditions; To assess change in patient-reported quality of life and functional vision over time; To compare the impact of different treatments on quality of life and functional vision; To assess change in patient-reported quality of life and functional vision in response to treatment; To determine associations between quality of life / functional vision scores and specific clinical and demographic characteristics. A Study to Evaluate a Color Test for Patients with Optic Nerve Diseases Rochester, Minn. The purpose of this study is to evaluate the clinical utility of a quantitative test to measure how color saturation appears in patients with diseases of the optive nerve. Exparel Injection for Postoperative Orbital Pain Rochester, Minn. After surgery to remove the eye, either by enucleation or evisceration, patients have variable levels of pain for several postoperative days. Some patients have almost no discomfort while others require significant amounts of oral narcotics and report pain of 10 out of 10 on a numerical rating scale. The current operative standard is to infiltrate the eye socket with 0.5% bupivacaine during surgery leading to several hours of postoperative analgesia. In 2011, Pacira Pharmaceuticals released a bupivacaine liposomal injectable suspension (Exparel, 1.3%) which offers sustained release of bupivacaine giving postoperative pain control for up to 72 hours. This medication has been used in numerous surgeries including inguinal hernia repair, hemorrhoidectomy, bunionectomy, breast reconstruction, and orthopedic surgery, and the literature reports improved pain control, decreased use of oral opioids, and increased patient satisfaction. There are no reports of the use of Exparel in the ophthalmic literature. The investigators propose a randomized, controlled trial to compare the postoperative pain control offered by sustained release bupivacaine to that offered by standard plain bupivacaine after enucleation or evisceration. A Study to Evaluate Optical Coherence Tomography (OCT) and OCT Angiography (OCTA) Imaging In Supine Patient Rochester, Minn. The purpose of this study is to determine if a relay lens and right angle mirror can be used in conjunction with an FDA-approved optical coherence tomography (OCT) unit to allow imaging in supine patients. A Study Randomized Trial to Evaluate Sequential vs Simultaneous Spectacles Plus Patching for Amblyopia in Children 3 to < 13 Years Old Rochester, Minn. The purpose of this study is to determine whether simultaneous treatment with spectacles and patching has an equivalent VA outcome compared with sequential treatment, first with spectacles alone, followed by patching (if needed), for previously untreated amblyopia in children 3 to < 13 years of age. A Study to Assess for Changes in Optic Nerve Structure and Function due to Changes in Cerebrospinal Fluid Pressure Rochester, Minn. The purpose of this study is to assess for changes in the structure and function of the optic nerve caused by changes in cerebrospinal fluid pressure. A Study to Evaluate Visual Function in Fuchs Endothelial Corneal Dystrophy Rochester, Minn. The purpose of this study is to determine visual function in patients with Fuchs Endothelial Corneal Dystrophy (FECD) to understand when in the course of disease patients are affected by compromised vision. Evaluating Optic Nerve Disease with OCT Angiography Rochester, Minn. The purpose of this study is to determine if optical coherence tomography (OCT) angiography is able to distinguish different causes of optic neuropathy. A Study to Analyze Waste Specimens from the Eye After Surgery Rochester, Minn. The purpose of this study is to learn about cell function in different tissues of the eye in various ocular diseases via transcriptomics in the Mayo Clinic laboratory. Numeración de páginas Estudios clínicos Ir a página 11 Ir a página 22 SiguientePróxima página A continuación, se enumeran los ensayos clínicos actuales.18 estudios en Oftalmología (solo estudios abiertos). Filtra esta lista de estudios por sede, estatus, etc. A Study to Evaluate Advanced Ultrasound Techniques for Diagnosis of Giant Cell Arteritis Rochester, Minn. The purpose of this study is to find out if advanced ultrasound studies can be used to make a diagnosis of giant cell arteritis. Ultimately, we hope to be able to offer non-invasive diagnostic options as an alternative to biopsy to future patients who are being evaluated for giant cell arteritis. A Study to Evaluate Patient Reported Outcome Measures in Children with Eye Conditions Rochester, Minn. The objectives of this study are: To evaluate patient-reported quality of life and functional vision across the spectrum of pediatric eye conditions; To assess change in patient-reported quality of life and functional vision over time; To compare the impact of different treatments on quality of life and functional vision; To assess change in patient-reported quality of life and functional vision in response to treatment; To determine associations between quality of life / functional vision scores and specific clinical and demographic characteristics. A Study to Evaluate a Color Test for Patients with Optic Nerve Diseases Rochester, Minn. The purpose of this study is to evaluate the clinical utility of a quantitative test to measure how color saturation appears in patients with diseases of the optive nerve. Exparel Injection for Postoperative Orbital Pain Rochester, Minn. After surgery to remove the eye, either by enucleation or evisceration, patients have variable levels of pain for several postoperative days. Some patients have almost no discomfort while others require significant amounts of oral narcotics and report pain of 10 out of 10 on a numerical rating scale. The current operative standard is to infiltrate the eye socket with 0.5% bupivacaine during surgery leading to several hours of postoperative analgesia. In 2011, Pacira Pharmaceuticals released a bupivacaine liposomal injectable suspension (Exparel, 1.3%) which offers sustained release of bupivacaine giving postoperative pain control for up to 72 hours. This medication has been used in numerous surgeries including inguinal hernia repair, hemorrhoidectomy, bunionectomy, breast reconstruction, and orthopedic surgery, and the literature reports improved pain control, decreased use of oral opioids, and increased patient satisfaction. There are no reports of the use of Exparel in the ophthalmic literature. The investigators propose a randomized, controlled trial to compare the postoperative pain control offered by sustained release bupivacaine to that offered by standard plain bupivacaine after enucleation or evisceration. A Study to Evaluate Optical Coherence Tomography (OCT) and OCT Angiography (OCTA) Imaging In Supine Patient Rochester, Minn. The purpose of this study is to determine if a relay lens and right angle mirror can be used in conjunction with an FDA-approved optical coherence tomography (OCT) unit to allow imaging in supine patients. A Study Randomized Trial to Evaluate Sequential vs Simultaneous Spectacles Plus Patching for Amblyopia in Children 3 to < 13 Years Old Rochester, Minn. The purpose of this study is to determine whether simultaneous treatment with spectacles and patching has an equivalent VA outcome compared with sequential treatment, first with spectacles alone, followed by patching (if needed), for previously untreated amblyopia in children 3 to < 13 years of age. A Study to Assess for Changes in Optic Nerve Structure and Function due to Changes in Cerebrospinal Fluid Pressure Rochester, Minn. The purpose of this study is to assess for changes in the structure and function of the optic nerve caused by changes in cerebrospinal fluid pressure. A Study to Evaluate Visual Function in Fuchs Endothelial Corneal Dystrophy Rochester, Minn. The purpose of this study is to determine visual function in patients with Fuchs Endothelial Corneal Dystrophy (FECD) to understand when in the course of disease patients are affected by compromised vision. Evaluating Optic Nerve Disease with OCT Angiography Rochester, Minn. The purpose of this study is to determine if optical coherence tomography (OCT) angiography is able to distinguish different causes of optic neuropathy. A Study to Analyze Waste Specimens from the Eye After Surgery Rochester, Minn. The purpose of this study is to learn about cell function in different tissues of the eye in various ocular diseases via transcriptomics in the Mayo Clinic laboratory. Numeración de páginas Estudios clínicos Ir a página 11 Ir a página 22 SiguientePróxima página Solicite una consulta Grupos especializadosInvestigación April 15, 2023 Comparte en: FacebookTwitter OftalmologíaPágina inicialdel departamentoSeccionesPanorama generalAnálisis y procedimientosEnfermedades tratadasMédicosGrupos especializadosEnsayos clínicosInvestigaciónCostos y seguroNoticias de Mayo ClinicRemisiones Investigación: los pacientes son la prioridad Mostrar la transcripción Para video Investigación: los pacientes son la prioridad [SUENA MÚSICA] Dr. Joseph Sirven, profesor de Neurología, Mayo Clinic: La misión de Mayo se centra en el paciente. La prioridad es el paciente. Aquí, la misión y la investigación se hacen para progresar en la forma de ayudar mejor al paciente y para asegurarnos de que el paciente sea la prioridad en la atención médica. De muchas maneras, esto equivale a un ciclo. Puede comenzar con algo tan simple como una idea que se desarrolla en un laboratorio, se traslada a la atención directa del paciente y, si todo sale bien y resulta útil o beneficioso, pasa a ser el método estándar. Creo que una de las características tan singulares de la forma de investigar en Mayo es la concentración en el paciente, y es lo que realmente le ayuda a captar la atención de todos. SeccionesSolicite una ConsultaPanorama generalAnálisis y procedimientosEnfermedades tratadasMédicosGrupos especializadosEnsayos clínicosInvestigaciónCostos y seguroNoticias de Mayo ClinicRemisiones ORG-20518365 Centros y departamentos médicos Oftalmología