Medicina cardiovascular

A continuación se enumeran ensayos clínicos actuales.

Filtrar esta lista de estudios según la ubicación, el estado del estudio y más.

1. A Study of Macitentan in Pulmonary Hypertension After Left Ventricular Assist Device Implantation

   Scottsdale/Phoenix, Ariz.

   The purpose of this study is to evaluate the effect of macitentan 10 mg on pulmonary vascular resistance as compared to placebo in subjects with pulmonary hypertension after left ventricular assist device (LVAD) implantation

    

2. Cardiovascular Effects of Energy Drinks in Healthy Adults

   Rochester, Minn.

   This study is being done to look at the cardiovascular response, if any, to intake of commercially available energy drink. We hypothesize that energy drink consumption compared to a control drink in healthy adults alters the cardiovascular hemodynamic system.

3. A Study for Sources of Pulmonary Congestion Associated with Heart Failure

   Rochester, Minn.

   The purpose of this study is to measure and identify chest fluid volumes associated with heart failure and to determine their impact on lung structure and function, and also assess the effect of body position on shifts in fluid and the effects of this on lung function, mechanics and gas exchange.

4. Transcatheter Aortic Valve Replacement to UNload the Left Ventricle in Patients With ADvanced Heart Failure (TAVR UNLOAD)

   Rochester, Minn.

   The objective of this study is to determine the safety and efficacy of transcatheter aortic valve replacement (TAVR) via a transfemoral approach in HF patients with moderate AS as compared with OHFT.

5. A Study of Inorganic Nitrite to Amplify the Benefits and Tolerability of Exercise Training in Heart Failure that has Preserved Ejection Fraction

   Rochester, Minn., Cannon Falls, Minn.

   Participants with heart failure with preserved ejection fraction will undergo 12 weeks of cardiac rehabilitation for exercise training (ET) and be randomized to either nebulized sodium nitrite inhalation solution or placebo inhalation solution (normal saline) through the training period. Study drug is administered 3 times daily during daytime hours with one of these doses being immediately prior to onset of ET sessions throughout the 12 week trial. The objective is to determine if the inhaled sodium nitrite improves the clinical responses and tolerability of ET.

6. Neural Circulatory Control and SUDEP Risk.

   Rochester, Minn.

   The investigators believe epilepsy alters the way the body controls blood pressure, heart rate and breathing, and these changes increase the risk of sudden unexpected death in patients with epilepsy (SUDEP). SUDEP-7 is a risk scoring tool which may correlate with these changes to the heart and blood vessels. This research study measures those differences which may help identify new markers to help predict those patients at greatest risk in the future.

7. Genetic Predictors of QT Prolongation with Anti-arrhythmic Medication

   Rochester, Minn.

   The purpose of this study is to assess the ability of common genetic variants in aggregate to predict drug-induced QT prolongation in patients being started on dofetilide. We will examine the predictiveness of a QT genotype score on QT prolongation in patients admitted for dofetilide initiation.
    

8. A Study of Oxygen Cost of Exercise in Patients with and without Heart Failure

   Rochester, Minn.

   This study is being done to: (1) develop a simple tool to assess breathing muscle performance; (2) measure the oxygen cost of breathing during exercise; (3) measure the respiratory muscle blood flow requirements of hyperpnea during exercise; and (4) to quantify the energy cost of exercise in relation to disease severity.

9. Ultrasound-based Technology (similar to standard clinical echocardiography) for Measuring the Stiffness of Heart Muscle and Peripheral Arteries

   Rochester, Minn.

   The purpose of this study is for evaluating an ultrasound-based technology (similar to standard clinical echocardiography) for measuring the stiffness of your heart muscle and your peripheral arteries. This type of information may prove to be clinically important.

10. A Study of Long-Term Outcomes of Cardiac Resynchronization Therapy Recipients with Congestive Heart Failure

    Rochester, Minn.

    The purpose of this study is to determine the long-term outcome of cardiac resynchronization therapy (CRT) recipients with congestive heart failure and any indications for CRT at Mayo Clinic.