Medicina cardiovascular

A continuación se enumeran ensayos clínicos actuales.

Filtrar esta lista de estudios según la ubicación, el estado del estudio y más.

1. Umbilical Cord Blood Collection and Processing for Pre-clinical Cardiac Regeneration

   Rochester, Minn., Eau Claire, Wis.

   The purpose of this study is to serve as the foundation to determine if a larger clinical study may be beneficial with the goal of establishing cord blood as a cell source to treat congenital heart disease for unhealthy babies.

2. A Study of Long-Term Outcomes of Cardiac Resynchronization Therapy Recipients with Congestive Heart Failure

   Rochester, Minn.

   The purpose of this study is to determine the long-term outcome of cardiac resynchronization therapy (CRT) recipients with congestive heart failure and any indications for CRT at Mayo Clinic.   

3. Ultrasound-based Technology (similar to standard clinical echocardiography) for Measuring the Stiffness of Heart Muscle and Peripheral Arteries

   Rochester, Minn.

   The purpose of this study is for evaluating an ultrasound-based technology (similar to standard clinical echocardiography) for measuring the stiffness of your heart muscle and your peripheral arteries. This type of information may prove to be clinically important.

4. A Study of Inorganic Nitrite to Amplify the Benefits and Tolerability of Exercise Training in Heart Failure that has Preserved Ejection Fraction

   Rochester, Minn., Cannon Falls, Minn.

   Participants with heart failure with preserved ejection fraction will undergo 12 weeks of cardiac rehabilitation for exercise training (ET) and be randomized to either nebulized sodium nitrite inhalation solution or placebo inhalation solution (normal saline) through the training period. Study drug is administered 3 times daily during daytime hours with one of these doses being immediately prior to onset of ET sessions throughout the 12 week trial. The objective is to determine if the inhaled sodium nitrite improves the clinical responses and tolerability of ET.

5. A Study to Evaluate Injectafer® as Treatment for Heart Failure with Iron Deficiency

   Rochester, Minn.

   The primary objective of this study is to determine the efficacy and safety of iron therapy using intravenous (IV) ferric carboxymaltose (FCM), relative to placebo, in the treatment of participants in heart failure with iron deficiency and with a reduced ejection fraction.

6. A Study of Oxygen Cost of Exercise in Patients with and without Heart Failure

   Rochester, Minn.

   This study is being done to: (1) develop a simple tool to assess breathing muscle performance; (2) measure the oxygen cost of breathing during exercise; (3) measure the respiratory muscle blood flow requirements of hyperpnea during exercise; and (4) to quantify the energy cost of exercise in relation to disease severity.

7. A Study of Biomarkers for Human Heart Failure

   Rochester, Minn.

   The purpose of this study is to attempt to establish the various ranges of proteins that can be assayed from the plasma and urine of patients with all classes of heart failure and MI (myocardial infarction).

8. 3D Echocardiography Volumetric Measurements in Patients with or without Valvular Heart Disease

   Rochester, Minn.

   The purpose of this study is to determine if 3D volumetric measurements will allow more robust quantification of valvular heart disease severity.

9. Genetic Predictors of QT Prolongation with Anti-arrhythmic Medication

   Rochester, Minn.

   The purpose of this study is to assess the ability of common genetic variants in aggregate to predict drug-induced QT prolongation in patients being started on dofetilide. We will examine the predictiveness of a QT genotype score on QT prolongation in patients admitted for dofetilide initiation.
    

10. A Study of Macitentan in Pulmonary Hypertension After Left Ventricular Assist Device Implantation

    Scottsdale/Phoenix, Ariz.

    The purpose of this study is to evaluate the effect of macitentan 10 mg on pulmonary vascular resistance as compared to placebo in subjects with pulmonary hypertension after left ventricular assist device (LVAD) implantation