Medicina cardiovascular

A continuación se enumeran ensayos clínicos actuales.

Filtrar esta lista de estudios según la ubicación, el estado del estudio y más.

1. A Study of Patients Who Underwent Intravascular Ultrasound to Create a Registry

   Rochester, Minn.

   Since Intravascular Ultrasound (IVUS) emerged as a significant tool for detection of early coronary atherosclerosis, we are maintaining an ongoing registry of those patients who have had this procedure done to provide more information regardint the successful interpretation of these intravascular ultrasound (IVUS). 

2. Ultrasound-based Technology (similar to standard clinical echocardiography) for Measuring the Stiffness of Heart Muscle and Peripheral Arteries

   Rochester, Minn.

   The purpose of this study is for evaluating an ultrasound-based technology (similar to standard clinical echocardiography) for measuring the stiffness of your heart muscle and your peripheral arteries. This type of information may prove to be clinically important.

3. Umbilical Cord Blood Collection and Processing for Pre-clinical Cardiac Regeneration

   Rochester, Minn., Eau Claire, Wis.

   The purpose of this study is to serve as the foundation to determine if a larger clinical study may be beneficial with the goal of establishing cord blood as a cell source to treat congenital heart disease for unhealthy babies.

4. 3D Echocardiography Volumetric Measurements in Patients with or without Valvular Heart Disease

   Rochester, Minn.

   The purpose of this study is to determine if 3D volumetric measurements will allow more robust quantification of valvular heart disease severity.

5. Genetic Predictors of QT Prolongation with Anti-arrhythmic Medication

   Rochester, Minn.

   The purpose of this study is to assess the ability of common genetic variants in aggregate to predict drug-induced QT prolongation in patients being started on dofetilide. We will examine the predictiveness of a QT genotype score on QT prolongation in patients admitted for dofetilide initiation.
    

6. A Study of Oxygen Cost of Exercise in Patients with and without Heart Failure

   Rochester, Minn.

   This study is being done to: (1) develop a simple tool to assess breathing muscle performance; (2) measure the oxygen cost of breathing during exercise; (3) measure the respiratory muscle blood flow requirements of hyperpnea during exercise; and (4) to quantify the energy cost of exercise in relation to disease severity.

7. Cardiovascular Effects of Energy Drinks in Healthy Adults

   Rochester, Minn.

   This study is being done to look at the cardiovascular response, if any, to intake of commercially available energy drink. We hypothesize that energy drink consumption compared to a control drink in healthy adults alters the cardiovascular hemodynamic system.

8. Transcatheter Aortic Valve Replacement to UNload the Left Ventricle in Patients With ADvanced Heart Failure (TAVR UNLOAD)

   Rochester, Minn.

   The objective of this study is to determine the safety and efficacy of transcatheter aortic valve replacement (TAVR) via a transfemoral approach in HF patients with moderate AS as compared with OHFT.

9. Saline-Enhanced Radiofrequency (SERF) Catheter Ablation for the Treatment of Ventricular Tachycardia

   Rochester, Minn.

   The purpose of this study is to demonstrate the technical feasibility of the Saline-Enhance Radiofrequency (SERF) Catheter and SERF Cardiac Ablation System to eliminate or control ventricular tachycardia (VT).

10. Safety, Tolerability and Pharmacodynamic Activity of Sotagliflozin in Hemodynamically Stable Patients With Worsening Heart Failure

    Rochester, Minn.

    Primary Objectives: - Assess the safety and tolerability of sotagliflozin in hemodynamically stable patients with worsening of heart failure, compared to placebo. - Estimate the effects of sotagliflozin on plasma volume changes in hemodynamically stable patients with worsening of heart failure, compared to placebo. Secondary Objectives: - Explore the effect of sotagliflozin on erythropoiesis, as assessed by changes in plasma erythropoietin levels, in hemodynamically stable patients with worsening of heart failure, compared to placebo. - Explore the effect of sotagliflozin on changes in plasma NT-proBNP levels, in hemodynamically stable patients with worsening of heart failure, compared to placebo.