Medicina cardiovascular

A continuación se enumeran ensayos clínicos actuales.

Filtrar esta lista de estudios según la ubicación, el estado del estudio y más.

1. Umbilical Cord Blood Collection and Processing for Pre-clinical Cardiac Regeneration

   Rochester, Minn., Eau Claire, Wis.

   The purpose of this study is to serve as the foundation to determine if a larger clinical study may be beneficial with the goal of establishing cord blood as a cell source to treat congenital heart disease for unhealthy babies.

2. A Study for Sources of Pulmonary Congestion Associated with Heart Failure

   Rochester, Minn.

   The purpose of this study is to measure and identify chest fluid volumes associated with heart failure and to determine their impact on lung structure and function, and also assess the effect of body position on shifts in fluid and the effects of this on lung function, mechanics and gas exchange.

3. A Study to Evaluate Optimal Target of Activated Clotting Time During Percutaneous Coronary Intervention and Outcomes

   Jacksonville, Fla., Rochester, Minn.

   The purpose of this study is to test the hypothesis that lower ACT target ranges, as compared to higher target ranges, are associated with reduced rates of bleeding. 

    

4. Randomized Placebo-controlled Trial of FCM as Treatment for Heart Failure With Iron Deficiency

   Rochester, Minn.

   The primary objective of this study is to determine the efficacy and safety of iron therapy using intravenous (IV) ferric carboxymaltose (FCM), relative to placebo, in the treatment of participants in heart failure with iron deficiency and with a reduced ejection fraction.

5. Transient Left Ventricular Apical Ballooning Syndrome (ABS) Registry

   La Crosse, Wis.

   The purpose of this study is to track the in-hospital and long-term event rates in this subset of patients.

6. A Study of Biomarkers for Human Heart Failure

   Rochester, Minn.

   The purpose of this study is to attempt to establish the various ranges of proteins that can be assayed from the plasma and urine of patients with all classes of heart failure and MI (myocardial infarction).

7. Genetic Predictors of QT Prolongation with Anti-arrhythmic Medication

   Rochester, Minn.

   The purpose of this study is to assess the ability of common genetic variants in aggregate to predict drug-induced QT prolongation in patients being started on dofetilide. We will examine the predictiveness of a QT genotype score on QT prolongation in patients admitted for dofetilide initiation.
    

8. A Study of Oxygen Cost of Exercise in Patients with and without Heart Failure

   Rochester, Minn.

   This study is being done to: (1) develop a simple tool to assess breathing muscle performance; (2) measure the oxygen cost of breathing during exercise; (3) measure the respiratory muscle blood flow requirements of hyperpnea during exercise; and (4) to quantify the energy cost of exercise in relation to disease severity.

9. 3D Echocardiography Volumetric Measurements in Patients with or without Valvular Heart Disease

   Rochester, Minn.

   The purpose of this study is to determine if 3D volumetric measurements will allow more robust quantification of valvular heart disease severity.

10. A Study to Evaluate the Safety and Effectiveness of the Multi-Electrode Radiofrequency Balloon Catheter for the Treatment of Symptomatic Paroxysmal Atrial Fibrillation

    Rochester, Minn.

    The primary objective of this clinical investigation is to demonstrate safety and effectiveness of the Multi-Electrode RF Balloon catheter for the treatment of drug refractory symptomatic paroxysmal atrial fibrillation.