Expandir el grupo de donantes con el trasplante haploidéntico

La investigación de Mayo Clinic sobre el trasplante haploidéntico (ha-plo-i-DÉN-ti-co) hizo posible que más personas puedan recibir este tratamiento para salvar sus vidas. El trasplante haploidéntico permite el uso de células madre de donantes que no son totalmente compatibles. Uno de los beneficios de este tipo de trasplante es su potencial para ampliar el número de donantes. La mayoría de las personas tienen un padre, un hermano o un hijo que podría servir potencialmente como donante parcialmente compatible (es compatible solo en un haplotipo HLA).

Los médicos de Mayo Clinic están llevando este tratamiento a la práctica clínica. Examinan cómo mejorar la recuperación y el funcionamiento del sistema inmunitario de las personas cuyos donantes de células madre no son totalmente compatibles. El éxito en este trabajo llevó a una gran expansión del acceso a los trasplantes, ya que los trasplantes haploidénticos se han convertido en una opción de tratamiento para determinados pacientes.

Estos son otros beneficios del trasplante haploidéntico:

  • Rápida disponibilidad de donante, reducción del tiempo entre la decisión de realizar el trasplante y la realización de este.
  • Reducción del riesgo de una complicación grave llamada enfermedad de injerto-contra-huésped.
  • Prevención de la reaparición de la enfermedad.
  • Prevención de infecciones y otras complicaciones.

Los investigadores de Mayo Clinic continúan investigando otros usos para el trasplante haploidéntico de médula ósea.

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Aug. 21, 2018
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