Andrew McKeon, M.B., B.Ch., M.D.

Specialized testing helps reverse effects of stiff-person syndrome

James and his wife Stephanie In July of 2018, James Kypuros woke up to find his toes clenched and claw-like, as if fisted. “It was a little bit weird walking this way, because you didn't have that balance of your toes extended,” recalls the 76-year-old Cedar Lake, Indiana resident. That summer marked the beginning of a host of debilitating symptoms that would defy significant treatment response until James came to Mayo Clinic, where specialized testing…