Publicaciones Imprimir Freedman BS, Bulte JWM, Conklin BR, Judge LM, Dwinell MR, Geurts AM, Sitton MJ, Mahajan V, Kiani S, Gersbach CA, Ebrahimkhani MR, Kelly JJ, Ronald JA, Morizane R, Gupta N, Shakeri-Zadeh A, Vo N, Saha K, Saxena S, Gamm DM, Sinha D, Tarantal AF, Vandsburger M, Matsubara A, Fu H, Tsai SQ, SCGE Dissemination and Coordinating Center Toolkit Team//SCGE Biological Effects Initiative. Monitoring biological effects of somatic cell genome editing. Nat Rev Genet. 2026 Jan 13 [Epub ahead of print] View PubMed Rees MJ, Dasari S, McPhail ED, Dispenzieri A, Charlesworth CM, Muchtar E, Gertz M, Gupta N, Anderson E, Quang SN, Dick C, Kumar S, Kourelis T. Proteomic shifts post-plasma cell therapy in AL amyloid plaques and potential implications for light chaindirected anti-fibril monoclonal antibodies. Haematologica. 2026 Jan 1; 111 (1):405-411 Epub 2025 July 24 View PubMed Robichaud JH, Afrin H, Torres VE, Gupta NR. Clinical Management of Tuberous Sclerosis: A Nephrologist's Perspective. Kidney360. 2025 Oct 1; 6 (10):1818-1825 Epub 2025 June 19 View PubMed Navin Gupta , Ke Zhang , Venkata Sabbisetti , Jian Shu , Ryuji Morizane . AAV for gene therapy drives a nephrotoxic response via NFkB in kidney organoids Signal Transduction and Targeted Therapy. 2025 Aug 8; 10(1):252. View PubMed Afrin H, Robichaud JH, Qamar U, Harris PC, Gupta N. Kidney organoids demonstrate that PTH1R drives a cystogenic cAMP-pPKA-pCREB axis in developmental polycystic kidney disease. Am J Physiol Renal Physiol. 2025 Aug 1; 329 (2):F257-F268 Epub 2025 July 02 View PubMed Afrin H, Qamar U, Robichaud JH, Ellabbad M, Harris PC, Gupta N. Kidney organoid models of polycystic kidney disease: challenges and future directions. Am J Physiol Renal Physiol. 2025 Jul 1; 329 (1):F143-F159 Epub 2025 June 11 View PubMed Yoon SH, Meyer MB, Arevalo C, Tekguc M, Zhang C, Wang JS, Castro Andrade CD, Strauss K, Sato T, Benkusky NA, Lee SM, Berdeaux R, Foretz M, Sundberg TB, Xavier RJ, Adelmann CH, Brooks DJ, Anselmo A, Sadreyev RI, Rosales IA, Fisher DE, Gupta N, Morizane R, Greka A, Pike JW, Mannstadt M, Wein MN. A parathyroid hormone/salt-inducible kinase signaling axis controls renal vitamin D activation and organismal calcium homeostasis. J Clin Invest. 2023 May 1; 133 (9) Epub 2023 May 01 View PubMed Carrisoza-Gaytan R, Kroll KT, Hiratsuka K, Gupta NR, Morizane R, Lewis JA, Satlin LM. Functional maturation of kidney organoid tubules: PIEZO1-mediated Ca(2+) signaling. Am J Physiol Cell Physiol. 2023 Mar 1; 324 (3):C757-C768 Epub 2023 Feb 06 View PubMed Susa K, Kobayashi K, Galichon P, Matsumoto T, Tamura A, Hiratsuka K, Gupta NR, Yazdi IK, Bonventre JV, Morizane R. ATP/ADP biosensor organoids for drug nephrotoxicity assessment. Front Cell Dev Biol. 2023; 11:1138504 Epub 2023 Mar 02 View PubMed Tekguc M, Gaal RCV, Uzel SGM, Gupta N, Riella LV, Lewis JA, Morizane R. Kidney organoids: a pioneering model for kidney diseases. Transl Res. 2022 Dec; 250:1-17 Epub 2022 June 21 View PubMed Hiratsuka K, Miyoshi T, Kroll KT, Gupta NR, Valerius MT, Ferrante T, Yamashita M, Lewis JA, Morizane R. Organoid-on-a-chip model of human ARPKD reveals mechanosensing pathomechanisms for drug discovery. Sci Adv. 2022 Sep 23; 8 (38):eabq0866 Epub 2022 Sept 21 View PubMed Gupta N, Morizane R. Kidney development to kidney organoids and back again. Semin Cell Dev Biol. 2022 Jul; 127:68-76 Epub 2021 Oct 07 View PubMed Gupta N, Matsumoto T, Hiratsuka K, Garcia Saiz E, Galichon P, Miyoshi T, Susa K, Tatsumoto N, Yamashita M, Morizane R. Modeling injury and repair in kidney organoids reveals that homologous recombination governs tubular intrinsic repair. Sci Transl Med. 2022 Mar 2; 14 (634):eabj4772 Epub 2022 Mar 02 View PubMed Rizki-Safitri A, Gupta N, Hiratsuka K, Kobayashi K, Zhang C, Ida K, Satlin LM, Morizane R. Live functional assays reveal longitudinal maturation of transepithelial transport in kidney organoids. Front Cell Dev Biol. 2022; 10:978888 Epub 2022 Aug 15 View PubMed Gupta N, Dilmen E, Morizane R.. 3D kidney organoids for bench-to-bedside translation Journal of Molecular Medicine.. 2020. Kishi S, Brooks CR, Taguchi K, Takaharu I, Mori Y, Akinfolarin A, Gupta N, Galichon P, Elias BC, Suzuki T, Wang Q, Gewin L, Morizane R. Bonventre JV. Proximal tubule ATR regulates DNA repair to prevent maladaptive renal injury responses. Journal of Clinical Investigation. 2019. Homan KA, Gupta N, Kroll KT, Kolesky DB, Skylar-Scott M, Miyoshi T, Mau D, Valerius MT, Ferrante T, Bonventre JV, Lewis JA, Morizane R. Flow-enhanced vascularization and maturation of kidney organoids in vitro. Nat Methods. 2019 Mar; 16 (3):255-262 Epub 2019 Feb 11 View PubMed Lemos DR, McMurdo M, Karaca G, Wilflingseder J, Leaf IA, Gupta N, Miyoshi T, Susa K, Johnson BG, Soliman K, Wang G, Morizane R, Bonventre JV, Duffield JS.. Interleukin-1ß activates a Myc-dependent metabolic switch in kidney stromal cells necessary for progressive tubulointerstitial fibrosis. J Am Soc Nephrol. 2018. Gupta N, Susa K, Yoda Y, Bonventre JV, Valerius MT, Morizane R. CRISPR/Cas9-based Targeted Genome Editing for the Development of Monogenic Diseases Models with Human Pluripotent Stem Cells. Curr Protoc Stem Cell Biol. 2018 May; 45 (1):e50 Epub 2018 Apr 26 View PubMed Gupta N, Susa K, Morizane R. Regenerative Medicine, Disease Modeling, and Drug Discovery in Human Pluripotent Stem Cell-derived Kidney Tissue. Eur Med J Reprod Health. 2017 Aug; 3 (1):57-67 View PubMed Sochol RD, Gupta NR, Bonventre JV. A Role for 3D Printing in Kidney-on-a-Chip Platforms. Curr Transplant Rep. 2016 Mar; 3 (1):82-92 Epub 2016 Jan 20 View PubMed Tsipotis E, Gupta NR, Raman G, Zintzaras E, Jaber BL. Bioavailability, Efficacy and Safety of Generic Immunosuppressive Drugs for Kidney Transplantation: A Systematic Review and Meta-Analysis. Am J Nephrol. 2016; 44 (3):206-18 Epub 2016 Aug 31 View PubMed PST-20561362 Inicio Publicaciones