Mark A. Edgar, M.D.

  1. Pathologist

Publicaciones

  1. Snow JT, Edgar MA, Halphen CR, Stanborough RO, Garner HW. Epithelioid osteoblastoma with secondary aneurysmal bone cyst and FOS gene rearrangement. Skeletal Radiol. 2022 Mar; 51 (3):673-679 Epub 2021 Aug 26
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  2. Overfield CJ, Edgar MA, Wessell DE, Wilke BK, Garner HW. NTRK-rearranged spindle cell neoplasm of the lower extremity: radiologic-pathologic correlation. Skeletal Radiol. 2022 Jan 14 [Epub ahead of print]
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  3. Zaver HB, Ghoz H, Azar A, Alexander LF, Toskich B, Edgar MA, Krishna M, Colibaseanu DT, Brahmbhatt B, Farraye FA. Inferior Mesenteric Arteriovenous Malformation Masquerading as Ulcerative Colitis. Am J Gastroenterol. 2021 Jun 1; 116 (6):1114
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  4. Cloutier JM, Charville GW, Mertens F, Sukov W, Fritchie K, Perry KD, Edgar M, Rowsey RA, Folpe AL. "Inflammatory Leiomyosarcoma" and "Histiocyte-rich Rhabdomyoblastic Tumor": a clinicopathological, immunohistochemical and genetic study of 13 cases, with a proposal for reclassification as "Inflammatory Rhabdomyoblastic Tumor". Mod Pathol. 2021 Apr; 34 (4):758-769 Epub 2020 Oct 22
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  5. Chen F, Desai MA, Cernigliaro JG, Edgar MA, Alexander LF. Perinephric myxoid pseudotumor of fat: A very rare entity that can mimic a renal cyst and retroperitoneal liposarcoma on imaging. Clin Imaging. 2021 Jan; 69:139-144 Epub 2020 July 01
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  6. Rooper LM, Uddin N, Gagan J, Brosens LAA, Magliocca KR, Edgar MA, Thompson LDR, Agaimy A, Bishop JA. Recurrent Loss of SMARCA4 in Sinonasal Teratocarcinosarcoma. Am J Surg Pathol. 2020 Oct; 44 (10):1331-1339
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  7. Benito-Martinez E, Galeano-Valle F, Gonzalez A, Edgar MA, Oprea-Ilies G, Ioachimescu AG, Pasquel FJ. Ectopic ACTH Syndrome With Association of Multiple Pulmonary Sclerosing Pneumocytomas and Multiple Carcinoid Tumorlets. J Endocr Soc. 2019 May 1; 3 (5):937-942 Epub 2019 Mar 18
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  8. Magliocca KR, Edgar MA, Corey A, Villari CR. Dedifferentiated chondrosarcoma of the larynx: Radiological, gross, microscopic and clinical features. Ann Diagn Pathol. 2017 Oct; 30:42-46 Epub 2017 May 16
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  9. Clay MR, Martinez AP, Weiss SW, Edgar MA. MDM2 and CDK4 Immunohistochemistry: Should It Be Used in Problematic Differentiated Lipomatous Tumors?: A New Perspective. Am J Surg Pathol. 2016 Dec; 40 (12):1647-1652
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  10. Rizer M, Singer AD, Edgar M, Jose J, Subhawong TK. The histological variants of liposarcoma: predictive MRI findings with prognostic implications, management, follow-up, and differential diagnosis. Skeletal Radiol. 2016 Sep; 45 (9):1193-204 Epub 2016 May 21
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  11. Geller RL, Hookim K, Sullivan HC, Stuart LN, Edgar MA, Reid MD. Cytologic features of angiosarcoma: A review of 26 cases diagnosed on FNA. Cancer Cytopathol. 2016 Sep; 124 (9):659-68 Epub 2016 Apr 18
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  12. Hart J, Gardner JM, Edgar M, Weiss SW. Epithelioid Schwannomas: An Analysis of 58 Cases Including Atypical Variants. Am J Surg Pathol. 2016 May; 40 (5):704-13
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  13. Clay MR, Martinez AP, Weiss SW, Edgar MA. MDM2 Amplification in Problematic Lipomatous Tumors: Analysis of FISH Testing Criteria. Am J Surg Pathol. 2015 Oct; 39 (10):1433-9
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  14. Linos K, Stuart L, Goncharuk V, Edgar M. Benign cutaneous biphasic hybrid tumor of perineurioma and cellular neurothekeoma: A case report expanding the clinical and histopathologic features of a recently described entity. Am J Dermatopathol. 2015 Apr; 37 (4):319-22
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  15. Sullivan HC, Edgar MA, Cohen C, Kovach CK, HooKim K, Reid MD. The utility of ERG, CD31 and CD34 in the cytological diagnosis of angiosarcoma: an analysis of 25 cases. J Clin Pathol. 2015 Jan; 68 (1):44-50 Epub 2014 Oct 28
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  16. Linos K, Carter JM, Gardner JM, Folpe AL, Weiss SW, Edgar MA. Myofibromas with atypical features: expanding the morphologic spectrum of a benign entity. Am J Surg Pathol. 2014 Dec; 38(12):1649-54.
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  17. Luther N, Zhou Z, Zanzonico P, Cheung NK, Humm J, Edgar MA, Souweidane MM. The potential of theragnostic (1)(2)(4)I-8H9 convection-enhanced delivery in diffuse intrinsic pontine glioma. Neuro Oncol. 2014 Jun; 16 (6):800-6 Epub 2014 Feb 12
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  18. Hart JL, Edgar MA, Gardner JM. Vascular tumors of bone. Semin Diagn Pathol. 2014 Jan; 31 (1):30-8 Epub 2014 Jan 07
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  19. Stuart LN, Gardner JM, Lauer SR, Monson DK, Parker DC, Edgar MA. Epithelioid sarcoma-like (pseudomyogenic) hemangioendothelioma, clinically mimicking dermatofibroma, diagnosed by skin biopsy in a 30-year-old man. J Cutan Pathol. 2013 Oct; 40 (10):909-13 Epub 2013 Aug 23
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  20. Huse JT, Edgar M, Halliday J, Mikolaenko I, Lavi E, Rosenblum MK. Multinodular and vacuolating neuronal tumors of the cerebrum: 10 cases of a distinctive seizure-associated lesion. Brain Pathol. 2013 Sep; 23 (5):515-24 Epub 2013 Feb 01
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  21. Hernandez A, Gardner J, Parker D, Monson D, Edgar M. Chondroid syringoma (mixed tumor) with tyrosine crystals. J Cutan Pathol. 2013 Jun; 40 (6):527-9
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  22. Marcus DM, Edgar MA, Hawk NN, Sullivan PS, Stapleford LJ. Small cell carcinoma of the anus in the setting of prior squamous dysplasia and carcinoma in situ. J Gastrointest Oncol. 2013 Jun; 4 (2):E1-4
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  23. Lauer SR, Edgar MA, Gardner JM, Sebastian A, Weiss SW. Soft tissue chordomas: a clinicopathologic analysis of 11 cases. Am J Surg Pathol. 2013 May; 37 (5):719-26
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  24. Edgar MA, Lauer SR, Bridge JA, Rizzo M. Soft tissue angiofibroma: report of 2 cases of a recently described tumor. Hum Pathol. 2013 Mar; 44 (3):438-41 Epub 2012 Dec 21
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  25. Wernicke AG, Edgar MA, Lavi E, Liu H, Salerno P, Bander NH, Gutin PH. Prostate-specific membrane antigen as a potential novel vascular target for treatment of glioblastoma multiforme. Arch Pathol Lab Med. 2011 Nov; 135 (11):1486-9
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  26. Scheithauer BW, Amrami KK, Folpe AL, Silva AI, Edgar MA, Woodruff JM, Levi AD, Spinner RJ. Synovial sarcoma of nerve. Hum Pathol. 2011 Apr; 42(4):568-77. Epub 2011 Feb 04.
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  27. Morozov A, Downey RJ, Healey J, Moreira AL, Lou E, Franceschino A, Dogan Y, Leung R, Edgar M, LaQuaglia M, Maki RG, Moore MA. Benign mesenchymal stromal cells in human sarcomas. Clin Cancer Res. 2010 Dec 1; 16 (23):5630-40
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  28. Gladdy RA, Qin LX, Moraco N, Edgar MA, Antonescu CR, Alektiar KM, Brennan MF, Singer S. Do radiation-associated soft tissue sarcomas have the same prognosis as sporadic soft tissue sarcomas? J Clin Oncol. 2010 Apr 20; 28 (12):2064-9 Epub 2010 Mar 22
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  29. Luther N, Cheung NK, Souliopoulos EP, Karampelas I, Bassiri D, Edgar MA, Guo HF, Pastan I, Gutin PH, Souweidane MM. Interstitial infusion of glioma-targeted recombinant immunotoxin 8H9scFv-PE38. Mol Cancer Ther. 2010 Apr; 9 (4):1039-46 Epub 2010 Apr 06
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  30. Maki RG, D'Adamo DR, Keohan ML, Saulle M, Schuetze SM, Undevia SD, Livingston MB, Cooney MM, Hensley ML, Mita MM, Takimoto CH, Kraft AS, Elias AD, Brockstein B, Blachere NE, Edgar MA, Schwartz LH, Qin LX, Antonescu CR, Schwartz GK. Phase II study of sorafenib in patients with metastatic or recurrent sarcomas. J Clin Oncol. 2009 Jul 1; 27 (19):3133-40 Epub 2009 May 18
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  31. Souweidane MM, Morgenstern PF, Christos PJ, Edgar MA, Khakoo Y, Rutka JT, Dunkel IJ. Intraoperative arachnoid and cerebrospinal fluid sampling in children with posterior fossa brain tumors. Neurosurgery. 2009 Jul; 65 (1):72-8; discussion 78
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  32. Rabbani F, Fine RG, D'Adamo D, Edgar M, Akin O, Paty P. Pure primary prostatic osteosarcoma arising in a non-irradiated prostate. Urol Int. 2009; 83 (2):236-8 Epub 2009 Sept 10
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  33. Luther N, Cheung NK, Dunkel IJ, Fraser JF, Edgar MA, Gutin PH, Souweidane MM. Intraparenchymal and intratumoral interstitial infusion of anti-glioma monoclonal antibody 8H9. Neurosurgery. 2008 Dec; 63 (6):1166-74; discussion 1174
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  34. Yoshida A, Edgar MA, Garcia J, Meyers PA, Morris CD, Panicek DM. Primary desmoplastic small round cell tumor of the femur. Skeletal Radiol. 2008 Sep; 37(9):857-62. Epub 2008 May 10.
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  35. Momota H, Shih AH, Edgar MA, Holland EC. c-Myc and beta-catenin cooperate with loss of p53 to generate multiple members of the primitive neuroectodermal tumor family in mice. Oncogene. 2008 Jul 24; 27 (32):4392-401 Epub 2008 Mar 31
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  36. Polydorides AD, Perry A, Edgar MA. Large cell medulloblastoma with myogenic and melanotic differentiation: a case report with molecular analysis. J Neurooncol. 2008 Jun; 88 (2):193-7
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  37. Idowu MO, Rosenblum MK, Wei XJ, Edgar MA, Soslow RA. Ependymomas of the central nervous system and adult extra-axial ependymomas are morphologically and immunohistochemically distinct--a comparative study with assessment of ovarian carcinomas for expression of glial fibrillary acidic protein. Am J Surg Pathol. 2008 May; 32 (5):710-8
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  38. Becher OJ, Hambardzumyan D, Fomchenko EI, Momota H, Mainwaring L, Bleau AM, Katz AM, Edgar M, Kenney AM, Cordon-Cardo C, Blasberg RG, Holland EC. Gli activity correlates with tumor grade in platelet-derived growth factor-induced gliomas. Cancer Res. 2008 Apr 1; 68 (7):2241-9
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  39. Edgar MA, Rosenblum MK. The differential diagnosis of central nervous system tumors: a critical examination of some recent immunohistochemical applications. Arch Pathol Lab Med. 2008 Mar; 132 (3):500-9
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  40. Matushansky I, Hernando E, Socci ND, Mills JE, Matos TA, Edgar MA, Singer S, Maki RG, Cordon-Cardo C. Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway. J Clin Invest. 2007 Nov; 117 (11):3248-57
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  41. Laufer I, Edgar MA, Hartl R. Primary intraosseous paraganglioma of the sacrum: a case report. Spine J. 2007 Nov-Dec; 7 (6):733-8 Epub 2006 Dec 22
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  42. Barbashina V, Salazar P, Ladanyi M, Rosenblum MK, Edgar MA. Glioneuronal tumor with neuropil-like islands (GTNI): a report of 8 cases with chromosome 1p/19q deletion analysis. Am J Surg Pathol. 2007 Aug; 31 (8):1196-202
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  43. Panagiotakos G, Alshamy G, Chan B, Abrams R, Greenberg E, Saxena A, Bradbury M, Edgar M, Gutin P, Tabar V. Long-term impact of radiation on the stem cell and oligodendrocyte precursors in the brain. PLoS One. 2007 Jul 11; 2 (7):e588 Epub 2007 July 11
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  44. Lae M, Ahn EH, Mercado GE, Chuai S, Edgar M, Pawel BR, Olshen A, Barr FG, Ladanyi M. Global gene expression profiling of PAX-FKHR fusion-positive alveolar and PAX-FKHR fusion-negative embryonal rhabdomyosarcomas. J Pathol. 2007 Jun; 212 (2):143-51
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  45. Polydorides AD, Rosenblum MK, Edgar MA. Metastatic renal cell carcinoma to hemangioblastoma in von Hippel-Lindau disease. Arch Pathol Lab Med. 2007 Apr; 131 (4):641-5
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  46. Ellis SJ, Gordin S, Edgar MA, Morris CD. Multiple ipsilateral lower extremity masses in a 46-year-old man. Schwannomatosis. Clin Orthop Relat Res. 2007 Mar; 456:268-74
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  47. Edgar MA, Rosenblum MK. Mixed glioneuronal tumors: recently described entities. Arch Pathol Lab Med. 2007 Feb; 131 (2):228-33
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  48. Hormigo A, Gu B, Karimi S, Riedel E, Panageas KS, Edgar MA, Tanwar MK, Rao JS, Fleisher M, DeAngelis LM, Holland EC. YKL-40 and matrix metalloproteinase-9 as potential serum biomarkers for patients with high-grade gliomas. Clin Cancer Res. 2006 Oct 1; 12 (19):5698-704
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  49. Luther N, Edgar MA, Dunkel IJ, Souweidane MM. Correlation of endoscopic biopsy with tumor marker status in primary intracranial germ cell tumors. J Neurooncol. 2006 Aug; 79 (1):45-50 Epub 2006 Apr 06
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  50. Ganly I, Patel SG, Stambuk HE, Coleman M, Ghossein R, Carlson D, Edgar M, Shah JP. Solitary fibrous tumors of the head and neck: a clinicopathologic and radiologic review. Arch Otolaryngol Head Neck Surg. 2006 May; 132 (5):517-25
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  51. Rutland BM, Edgar MA, Horenstein MG. Hypomelanosis of Ito associated with precocious puberty. Pediatr Neurol. 2006 Jan; 34 (1):51-4
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  52. Prabhakaran S, Bramlage M, Edgar MA, Diamond B, Hardin JA, Volpe BT. Overwhelming leukoencephalopathy as the only sign of neuropsychiatric lupus. J Rheumatol. 2005 Sep; 32 (9):1843-5
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  53. Virtanen JO, Zabriskie JB, Siren V, Friedman JE, Lyons MJ, Edgar M, Vaheri A, Koskiniemi M. Co-localization of human herpes virus 6 and tissue plasminogen activator in multiple sclerosis brain tissue. Med Sci Monit. 2005 Mar; 11 (3):BR84-7
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  54. Renaud S, Hays AP, Brannagan TH 3rd, Sander HW, Edgar M, Weimer LH, Olarte MR, Dalakas MC, Xiang Z, Danon MJ, Latov N. Gene expression profiling in chronic inflammatory demyelinating polyneuropathy. J Neuroimmunol. 2005 Feb; 159 (1-2):203-14 Epub 2004 Dec 19
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  55. Souweidane MM, Occhiogrosso G, Mark EB, Edgar MA. Interstitial infusion of IL13-PE38QQR in the rat brain stem. J Neurooncol. 2004 May; 67 (3):287-93
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  56. Souweidane MM, Occhiogrosso G, Mark EB, Edgar MA, Dunkel IJ. Interstitial infusion of carmustine in the rat brain stem with systemic administration of O6-benzylguanine. J Neurooncol. 2004 May; 67 (3):319-26
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  57. Goldsmith HS, Wu W, Zhong J, Edgar M. Omental transposition to the brain as a surgical method for treating Alzheimer's disease. Neurol Res. 2003 Sep; 25 (6):625-34
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  58. Scognamiglio T, Hoda RS, Edgar MA, Hoda SA. The need for vigilance in the pathologic evaluation of sentinel lymph nodes: a report of two illustrative cases. Breast J. 2003 Sep-Oct; 9 (5):420-2
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  59. Occhiogrosso G, Edgar MA, Sandberg DI, Souweidane MM. Prolonged convection-enhanced delivery into the rat brainstem. Neurosurgery. 2003 Feb; 52 (2):388-93; discussion 393-4
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  60. Chen X, Hoda SA, Edgar MA. Cardiac rhabdomyoma. Arch Pathol Lab Med. 2002 Dec; 126 (12):1559
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  61. Takahashi RH, Milner TA, Li F, Nam EE, Edgar MA, Yamaguchi H, Beal MF, Xu H, Greengard P, Gouras GK. Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology. Am J Pathol. 2002 Nov; 161 (5):1869-79
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  62. Sandberg DI, Edgar MA, Souweidane MM. Effect of hyperosmolar mannitol on convection-enhanced delivery into the rat brain stem. J Neurooncol. 2002 Jul; 58 (3):187-92
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  63. Lasco MS, Jordan TJ, Edgar MA, Petito CK, Byne W. A lack of dimorphism of sex or sexual orientation in the human anterior commissure. Brain Res. 2002 May 17; 936 (1-2):95-8
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  64. Sandberg DI, Edgar MA, Souweidane MM. Convection-enhanced delivery into the rat brainstem. J Neurosurg. 2002 May; 96 (5):885-91
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  65. Takahashi RH, Nam EE, Edgar M, Gouras GK. Alzheimer beta-amyloid peptides: normal and abnormal localization. Histol Histopathol. 2002 Jan; 17 (1):239-46
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  66. Horska A, Ulug AM, Melhem ER, Filippi CG, Burger PC, Edgar MA, Souweidane MM, Carson BS, Barker PB. Proton magnetic resonance spectroscopy of choroid plexus tumors in children. J Magn Reson Imaging. 2001 Jul; 14 (1):78-82
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  67. Sandberg DI, Edgar MA, Resch L, Rutka JT, Becker LE, Souweidane MM. MIB-1 staining index of pediatric meningiomas. Neurosurgery. 2001 Mar; 48 (3):590-5; discussion 595-7
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  68. Filippi CG, Edgar MA, Ulug AM, Prowda JC, Heier LA, Zimmerman RD. Appearance of meningiomas on diffusion-weighted images: correlating diffusion constants with histopathologic findings. AJNR Am J Neuroradiol. 2001 Jan; 22 (1):65-72
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  69. Bruno MK, Winterkorn JM, Edgar MA, Kamal A, Stubgen JP. Unilateral Adie pupil as sole ophthalmic sign of anti-Hu paraneoplastic syndrome. J Neuroophthalmol. 2000 Dec; 20 (4):248-9
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  70. Zonenshayn M, Edgar MA, Lavyne MH. Removal of a lumbar melanotic schwannoma via the far-lateral approach in a patient with Carney complex. Case report. J Neurosurg. 2000 Apr; 92 (2 Suppl):241-5
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  71. Byne W, Lasco MS, Kemether E, Shinwari A, Edgar MA, Morgello S, Jones LB, Tobet S. The interstitial nuclei of the human anterior hypothalamus: an investigation of sexual variation in volume and cell size, number and density. Brain Res. 2000 Feb 21; 856 (1-2):254-8
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  72. Canoll P, Edgar M. Crystalline cytoplasmic inclusions in an anaplastic oligodendroglioma. Ultrastructural Pathology. 2000; 24(6):423-5. Epub 1952 Jan 11.
  73. Gouras GK, Tsai J, Naslund J, Vincent B, Edgar M, Checler F, Greenfield JP, Haroutunian V, Buxbaum JD, Xu H, Greengard P, Relkin NR. Intraneuronal Abeta42 accumulation in human brain. Am J Pathol. 2000 Jan; 156 (1):15-20
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  74. Friedman JE, Lyons MJ, Cu G, Ablashl DV, Whitman JE, Edgar M, Koskiniemi M, Vaheri A, Zabriskie JB. The association of the human herpesvirus-6 and MS. Mult Scler. 1999 Oct; 5 (5):355-62
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  75. Sotsky TK, Chiou AC, Jacobson I, Leonard M, Edgar M, Bertagnolli MM. Sclerosing mesenteritis presenting with ascites and peritoneal infiltration. Contemporary Surgery. 1999; 55(3):132-4.
  76. Pincus DW, Keyoung HM, Harrison-Restelli C, Goodman RR, Fraser RA, Edgar M, Sakakibara S, Okano H, Nedergaard M, Goldman SA. Fibroblast growth factor-2/brain-derived neurotrophic factor-associated maturation of new neurons generated from adult human subependymal cells. Ann Neurol. 1998 May; 43 (5):576-85
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  77. Edgar M, Heier L. HIV/AIDS case histories: diagnostic problems. Varicella-zoster encephalitis. AIDS Patient Care STDS. 1998 Jan; 12 (1):61-2
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  78. Sun DY, Edgar M, Rubin M. Hemiparetic acute myopathy of intensive care progressing to triplegia. Arch Neurol. 1997 Nov; 54 (11):1420-2
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  79. MacGowan DJ, Delanty N, Petito F, Edgar M, Mastrianni J, DeArmond SJ. Isolated myoclonic alien hand as the sole presentation of pathologically established Creutzfeldt-Jakob disease: a report of two patients. J Neurol Neurosurg Psychiatry. 1997 Sep; 63 (3):404-7
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  80. Soslow RA, Edgar MA, Schron D, Chung MH. Glial and neuronal neoplasms in ovarian teratomas Pathol Int. 1996; 46(s1):372.
  81. Relkin NR, Edgar MA, Gouras GK, Gandy SE, Goldsmith HS. Decreased senile plaque density in Alzheimer neocortex adjacent to an omental transposition. Neurol Res. 1996 Aug; 18 (4):291-4; discussion 295-6
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  82. Triggs WJ, Edgar MA. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 36-1995. A 61-year-old man with increasing weakness and atrophy of all extremities. N Engl J Med. 1995 Nov 23; 333 (21):1406-12
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  83. Tatter SB, Edgar MA, Klibanski A, Swearingen B. Symptomatic salivary-rest cyst of the sella turcica. Acta Neurochir (Wien). 1995; 135 (3-4):150-3
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PST-20523097