Description and Brand Names

Drug information provided by: Merative, Micromedex®

US Brand Name

  1. Xipere

Descriptions


Triamcinolone suprachoroidal injection is used to treat macular edema associated with uveitis (redness, pain, or swelling of the eye). Macular edema is swelling in the back of the eye and may cause vision loss.

This medicine is to be given only by or under the direct supervision of your doctor.

This product is available in the following dosage forms:

  • Suspension

Before Using

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of triamcinolone suprachoroidal injection in the pediatric population. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of triamcinolone suprachoroidal injection in the elderly.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Drug Interactions

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

  • Desmopressin
  • Rotavirus Vaccine, Live

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Aldesleukin
  • Aspirin
  • Atazanavir
  • Balofloxacin
  • Bemiparin
  • Besifloxacin
  • Carbamazepine
  • Ceritinib
  • Ciprofloxacin
  • Cobicistat
  • Cosyntropin
  • Darunavir
  • Enoxacin
  • Fleroxacin
  • Flumequine
  • Gatifloxacin
  • Gemifloxacin
  • Levofloxacin
  • Lomefloxacin
  • Lutetium Lu 177 Dotatate
  • Macimorelin
  • Moxifloxacin
  • Nadifloxacin
  • Nadroparin
  • Nirmatrelvir
  • Norfloxacin
  • Ofloxacin
  • Pazufloxacin
  • Pefloxacin
  • Prulifloxacin
  • Ritonavir
  • Rufloxacin
  • Sargramostim
  • Somatrogon-ghla
  • Sparfloxacin
  • Tosufloxacin

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Alcuronium
  • Atracurium
  • Auranofin
  • Fosphenytoin
  • Gallamine
  • Hexafluorenium
  • Licorice
  • Metocurine
  • Phenytoin
  • Primidone
  • Saiboku-To

Other Interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Fungal eye infection or
  • Herpes infection of the eye, active or
  • Mycobacterial eye infection or
  • Vaccinia (smallpox) eye infection or
  • Varicella (chickenpox) eye infection—Should not be used in patients with these conditions.
  • Herpes infection of the eye, history of or
  • Thyroid problems (eg, overactive or underactive thyroid)—Use with caution. May make these conditions worse.

Proper Use

Your eye doctor (ophthalmologist) will give you this medicine in a hospital or clinic. It is given as a shot into the eye.

Precautions

Your eye doctor will want to check your progress at regular visits, especially during the first few days after you receive this medicine, to make sure this medicine is working properly and to check for unwanted effects.

Serious eye problems (eg, cataracts, glaucoma, detached retina, eye infection or swelling) may occur after receiving this medicine. Check with your eye doctor right away if you have a change in vision or the eye becomes red, sensitive to light, or painful. Also, tell your doctor if you feel an increased pressure in the eye.

This medicine may cause endocrine problems (eg, HPA axis suppression, Cushing syndrome, high blood sugar). These problems may occur if you are receiving this medicine for a long time or if you suddenly stopped receiving it. Talk with your doctor if you have any concerns about this.

Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

  1. Blindness
  2. blurred vision
  3. change in vision
  4. eye pain
  5. increased pressure in the eye
  6. loss of vision
  7. seeing flashes or sparks of light
  8. seeing floating spots before the eyes, or a veil or curtain appearing across part of vision

Less common

  1. Bloody eye
  2. change in color vision
  3. difficulty seeing at night
  4. drooping upper eyelids
  5. increased sensitivity of the eyes to sunlight
  6. painful irritation of the clear front part of the eye
  7. swelling or redness of the eye or inside of the eyelids
  8. tearing

Incidence not known

  1. Backache
  2. darkening of the skin
  3. diarrhea
  4. dizziness
  5. dry mouth
  6. facial hair growth in females
  7. fainting
  8. flushed, dry skin
  9. fractures
  10. fruit-like breath odor
  11. full or round face, neck, or trunk
  12. increased hunger
  13. increased thirst or urination
  14. irritability
  15. loss of appetite
  16. loss of sexual desire or ability
  17. menstrual irregularities
  18. mental depression
  19. muscle wasting
  20. nausea
  21. sweating
  22. trouble breathing
  23. unexplained weight loss
  24. unusual tiredness or weakness
  25. vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  1. Headache

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Portions of this document last updated: May 01, 2024

Original article: https://www.mayoclinic.org/drugs-supplements/triamcinolone-intraocular-route/description/drg-20524772