X-linked agammaglobulinemia

By Mayo Clinic Staff
Sept. 17, 2026

Research

At Mayo Clinic, scientists and doctors at the Primary Immunodeficiency Center in Minnesota conduct research on X-linked agammaglobulinemia (XLA) and other primary immunodeficiencies.

Researchers and doctors trained in immune system conditions, genetics and other fields conduct basic and clinical research aimed at developing new treatments for XLA. Treatments under study include stem cell transplantation and gene therapy.

Publications

See a list of publications about X-linked agammaglobulinemia by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

  1. X-linked agammaglobulinemia. American Academy of Allergy, Asthma & Immunology. https://www.aaaai.org/conditions-treatments/primary-immunodeficiency-disease/x-linked-agammaglobulinemia. Accessed Nov. 19, 2025.
  2. Hernandez-Trujillo VP. Agammaglobulinemia. https://www.uptodate.com/contents/search. Accessed Nov. 19, 2025.
  3. Ballow M, et al., eds. Immune Deficiency Foundation Patient & Family Handbook for Primary Immunodeficiency Diseases. 6th ed. Immune Deficiency Foundation. https://primaryimmune.org/publication/patients-and-families/idf-patient-family-handbook-primary-immunodeficiency-diseases-6th. Accessed Nov. 19, 2025.
  4. Ferri FF. Primary immunodeficiency disease. In: Ferri's Clinical Advisor 2026. Elsevier; 2026. https://www.clinicalkey.com. Accessed Nov. 19, 2025.
  5. Keller M. Inborn errors of immunity (primary immunodeficiencies): Overview of management. https://www.uptodate.com/contents/search. Accessed Nov. 19, 2025.