Wolff-Parkinson-White (WPW) syndrome

By Mayo Clinic Staff
June 19, 2026

Research

Mayo Clinic doctors and scientists are studying ways to improve diagnosis and treatment of heart arrhythmias, including WPW syndrome. The Heart Rhythm Disease Program in the Cardiovascular Research Center focuses on several areas related to irregular heartbeats, called cardiac arrhythmias.

Publications

See a list of publications about Wolff-Parkinson-White syndrome by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

  1. Di Biase L, et al. Wolff-Parkinson-White syndrome: Anatomy, epidemiology, clinical manifestations, and diagnosis. https://www.uptodate.com/contents/search. Accessed June 11, 2025.
  2. Ferri FF. Wolff-Parkinson-White syndrome. In: Ferri's Clinical Advisor 2025. Elsevier; 2025. https://www.clinicalkey.com. Accessed June 11, 2025.
  3. Other heart rhythm disorders. American Heart Association. https://www.heart.org/en/health-topics/arrhythmia/about-arrhythmia/other-heart-rhythm-disorders. Accessed June 11, 2025.
  4. AskMayoExpert. Supraventricular tachycardia. Mayo Clinic; 2024.
  5. Escudero CA, et al. Loss of ventricular preexcitation during noninvasive testing does not exclude high-risk accessory pathways: A multicenter study of WPW in children. Heart Rhythm. 2020; doi:10.1016/j.hrthm.2020.05.035.
  6. How the heart works. National Heart, Lung, and Blood Institute. https://www.nhlbi.nih.gov/health/heart. Accessed June 11, 2025.
  7. Di Biase L, et al. Treatment of symptomatic arrhythmias associated with the Wolff-Parkinson-White syndrome. https://www.uptodate.com/contents/search. Accessed June 11, 2025.
  8. Dubin AM. Clinical features and diagnosis of supraventricular tachycardia (SVT) in children. https://www.uptodate.com/contents/search. Accessed June 11, 2025.
  9. Harris KM. Allscripts EPSi. Mayo Clinic. May 8, 2025.
  10. Arrhythmia. National Heart, Lung, and Blood Institute. https://www.nhlbi.nih.gov/health/arrhythmias. Accessed June 11, 2025.
  11. Atrial fibrillation and Wolff-Parkinson-White syndrome (WPW syndrome). Merck Manual Professional Version. https://www.merckmanuals.com/professional/cardiovascular-disorders/specific-cardiac-arrhythmias/atrial-fibrillation-and-wolff-parkinson-white-syndrome-wpw-syndrome Accessed June 11, 2025.
  12. Tachycardia: Fast heart rate. American Heart Association. https://www.heart.org/en/health-topics/arrhythmia/about-arrhythmia/tachycardia--fast-heart-rate. Accessed June 11, 2025.