Seizures

Nov. 01, 2024

Research

Mayo Clinic experts trained in neurology, neurosurgery and other areas study genetics, risks, potential diagnostic tests and treatments for seizures and epilepsy.

Mayo Clinic researchers have developed and studied a wide range of diagnostic and treatment tools for seizures and epilepsy. These tools include MRI, subtraction ictal SPECT coregistered to MRI (SISCOM), electroencephalography, ketogenic diet, deep brain stimulation, epilepsy surgery and many others.

Read more about Mayo Clinic research in epilepsy and bioelectronics neurophysiology and engineering.

Publications

See a list of publications about seizures by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

  1. Schachter SC. Evaluation and management of the first seizure in adults. https://www.uptodate.com/contents/search. Accessed July 31, 2024.
  2. AskMayoExpert. First seizure (adult). Mayo Clinic, 2024.
  3. Epilepsy and seizures. National Institute of Neurological Disorders and Stroke. https://www.ninds.nih.gov/health-information/disorders/epilepsy-and-seizures#. Accessed July 31, 2024.
  4. Ferri FF. New-onset seizures. In: Ferri's Clinical Advisor 2025. Elsevier; 2025. https://www.clinicalkey.com. Accessed July 31, 2024.
  5. Walls RM, et al. Seizure. In: Rosen's Emergency Medicine. 10 ed. Elsevier; 2023. https://www.clinicalkey.com. Accessed July 31, 2024.
  6. Seizure first aid. Epilepsy Foundation. https://www.epilepsy.com/recognition/first-aid-resources#General-First-Aid-for-All-Seizure-Types. Accessed Aug. 1, 2024.
  7. Deep brain stimulation for movement disorders. National Institute of Neurological Disorders and Stroke. https://www.ninds.nih.gov/health-information/disorders/deep-brain-stimulation-movement-disorders. Accessed Aug. 1, 2024.
  8. First aid for seizures. Centers for Disease Control and Prevention. https://www.cdc.gov/epilepsy/first-aid-for-seizures/?CDC_AAref_Val=https://www.cdc.gov/epilepsy/about/first-aid.htm. Accessed Aug. 1, 2024.
  9. Neurological diagnostic tests and procedures. National Institute of Neurological Disorders and Stroke.https://www.ninds.nih.gov/health-information/disorders/neurological-diagnostic-tests-and-procedures#. Accessed Aug. 1, 2024.
  10. Haider HA, et al. Neuroimaging in the evaluation of seizures and epilepsy. https://www.uptodate.com/contents/search. Accessed Aug 1, 2024.
  11. Brinkmann BH, et al. Seizure diaries and forecasting with wearables: Epilepsy monitoring outside the clinic. Frontiers in Neurology. 2021: doi:10.3389/fneur.2021.690404
  12. Lescrauwaet E, et al. Recent advance in the use of focused ultrasound as a treatment for epilepsy. Frontiers in Neuroscience. 2022; doi:10.3389/fnins.2022.886584.
  13. Ritesh N. Allscripts EPSi. Mayo Clinic. Aug. 13, 2024.
  14. Jankovic J, et al., eds. Epilepsies. In: Bradley and Daroff's Neurology in Clinical Practice. 8th ed. Elsevier; 2022. https://www.clinicalkey.com. Accessed Aug. 1, 2024.
  15. Kossoff EH. Ketogenic dietary therapies for treatment of epilepsy. https://www.uptodate.com/contents/search. Accessed Aug. 1, 2024.
  16. Giussani G, et al. Sudden unexpected death in epilepsy: A critical review of the literature. Epilepsia Open. 2023; doi:10.1002/epi4.12722.