Idiopathic hypersomnia

By Mayo Clinic Staff
Oct. 30, 2024

Research

Mayo Clinic doctors and researchers study possible treatments for idiopathic hypersomnia and other sleep conditions and conduct clinical trials.

Publications

See a list of publications about idiopathic hypersomnia by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

  1. Chervin RD. Idiopathic hypersomnia. https://www.uptodate.com/contents/search. Accessed May 12,2022.
  2. Idiopathic hypersomnia. Genetic and Rare Diseases Information Center. https://rarediseases.info.nih.gov/diseases/8737/idiopathic-hypersomnia. Accessed May 12, 2022.
  3. Trotti LM, et al. Idiopathic hypersomnia and other hypersomnia syndromes. Neurotherapeutics.2021; doi:10.1007/s13311-020-00919-1.
  4. Dauvilliers Y, et al. Safety and efficacy of lower-sodium oxybate in adults with idiopathic hypersomnia: A phase 3, placebo-controlled, double-blind, randomized withdrawal study. Lancet Neurology. 2022; doi:10.1016/S1474-4422(21)00368-9.
  5. Littner MR, et al. Practice parameters for clinical use of the multiple sleep latency test and the maintenance of wakefulness test. Sleep. 2005; doi:10.1093/sleep/28.1.113.
  6. Inoue Y, et al. Efficacy and safety of modafinil in patients with idiopathic hypersomnia without long sleep time: A multicenter, randomized, double-blind, placebo-controlled, parallel-group comparison study. Sleep. 2021; doi:10.1016/j.sleep.2021.01.018.
  7. Sowa NA. Idiopathic hypersomnia and hypersomnolence disorder: A systematic review of the literature. Psychosomatics. 2016; doi:10.1016/j.psym.2015.12.006.
  8. Saini P, et al. Hypersomnia evaluation, treatment and social and economic aspects. Sleep Medicine Clinics. 2017; doi:10.1016/j.jsmc.2016.10.013.
  9. Nguyen H. AllScripts EPSi. Mayo Clinic. April 20, 2022.
  10. Maski K, et al. Treatment of central disorders of hypersomnolence: An American Academy of Sleep Medicine clinical practice guideline. Journal of Clinical Sleep Medicine. 2021; doi:10.5664/jcsm.9328.