Generalized anxiety disorder

By Mayo Clinic Staff
May 27, 2026

Research

Researchers are working to better diagnose and treat anxiety disorders in children and teenagers. They're learning about the factors that lead to anxiety disorders. And they're taking images to look into how the nervous system affects anxiety disorders. Studies include randomized controlled trials comparing versions of cognitive behavior therapy for childhood anxiety disorders. These studies also are looking into how to use technology to provide treatment.

Researchers also are working to better assess and treat anxiety disorders for adults in the primary care setting.

Publications

See a list of publications about anxiety disorders by Mayo doctors on PubMed, a service of the National Library of Medicine.

  1. Generalized anxiety disorder. In: Diagnostic and Statistical Manual of Mental Disorders DSM-5-TR. 5th ed. American Psychiatric Association; 2022. https://dsm.psychiatryonline.org. Accessed Dec. 6, 2023.
  2. Gabbard GO, ed. Generalized anxiety disorder. In: Gabbard's Treatments of Psychiatric Disorders. 5th ed. Arlington, Va.: American Psychiatric Association; 2014. http://psychiatryonline.org/doi/book/10.1176/appi.books.9781585625048. Accessed June 26, 2017.
  3. Baldwin D. Generalized anxiety disorder in adults: Epidemiology, pathogenesis, clinical manifestations, course, assessment, and diagnosis. https//:www.uptodate.com/contents/search. Accessed Dec. 6, 2023.
  4. Craske M, et al. Generalized anxiety disorder in adults: Management. https://www.uptodate.com/contents/search. Accessed Dec. 6, 2023.
  5. Craske M. Psychotherapy for generalized anxiety disorder in adults. https//:www.uptodate.com/contents/search. Accessed June 26, 2017.
  6. Bystritsky A. Pharmacotherapy for generalized anxiety disorder in adults. https//:www.uptodate.com/contents/search. Accessed June 26, 2017.
  7. Bystritsky A. Complementary and alternative treatments for anxiety symptoms and disorders: Herbs and medications. https//:www.uptodate.com/contents/search. Accessed June 20, 2017.
  8. Bystritsky A. Complementary and alternative treatments for anxiety symptoms and disorders: Physical, cognitive, and spiritual interventions. https//:www.uptodate.com/contents/search. Accessed June 20, 2017.
  9. Generalized anxiety disorder: When worry gets out of control. National Institute of Mental Health. https://www.nimh.nih.gov/health/publications/generalized-anxiety-disorder-gad/index.shtml. Accessed June 26, 2017.
  10. Natural medicines in the clinical management of anxiety. Natural Medicines. https://naturalmedicines.therapeuticresearch.com. Accessed June 20, 2017.
  11. Anxiety disorders. Natural Medicines. https://naturalmedicines.therapeuticresearch.com. Accessed June 20, 2017.
  12. AskMayoExpert. Anxiety disorders. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2017. Accessed June 20, 2017.
  13. Valerian. Natural Medicines. https://naturalmedicines.therapeuticresearch.com. Accessed June 26, 2017.
  14. Facts for families: The anxious child. American Academy of Child and Adolescent Psychiatry. http://www.aacap.org/AACAP/Families_and_Youth/Facts_for_Families/Facts_for_Families_Pages/The_Anxious_Child_47.aspx. Accessed June 26, 2017.
  15. Brown A. Allscripts EPSi. Mayo Clinic, Rochester, Minn. April 21, 2017.
  16. Kava. Natural Medicines. https://naturalmedicines.therapeuticresearch.com. Accessed Dec. 6, 2023.
  17. Valerian. Natural Medicines. https://naturalmedicines.therapeuticresearch.com. Accessed Dec. 6, 2023.
  18. Passion flower. Natural Medicines. https://naturalmedicines.therapeuticresearch.com. Accessed Dec. 6, 2023.
  19. Stein MB, et al. Treating anxiety in 2017: Optimizing care to improve outcomes. JAMA. 2017;318:236.
  20. Medical review (expert opinion). Mayo Clinic. Dec. 28, 2023.