Departments and specialties

Mayo Clinic has one of the largest and most experienced practices in the United States, with campuses in Arizona, Florida and Minnesota. Staff skilled in dozens of specialties work together to ensure quality care and successful recovery.

Departments that treat this condition

Areas that research this condition


Mayo Clinic's Department of Ophthalmology has a strong tradition of advanced research to improve the diagnosis and treatment of cornea disorders, and is a leader in Fuchs' dystrophy research, from genetics of the disease to clinical management.

The common form of Fuchs' dystrophy begins in the 30s and 40s and accounts for the vast majority of cases in the United States. Mayo Clinic researchers discovered that 75% of these cases were associated with a specific genetic abnormality, a trinucleotide expansion repeat in a gene called transcription factor 4 (TCF4). Researchers at Mayo Clinic and elsewhere are now using this information to discover medical therapies that might slow or stop the progression of the disease. Mayo Clinic researchers have also described how to best use imaging techniques to help manage the disease in clinical practice, and to predict the prognosis of the disease.

Learn more about ongoing clinical trials at Mayo Clinic for people with Fuchs' dystrophy.


See a list of publications by Mayo Clinic authors on Fuchs' dystrophy on PubMed, a service of the National Library of Medicine.