Frontotemporal dementia

By Mayo Clinic Staff
April 17, 2026

Research

Mayo Clinic staff actively research frontotemporal dementia and related conditions. Researchers study risk factors, causes, diagnostic techniques and treatment options for frontotemporal dementia.

  • The Alzheimer's Disease Research Center is jointly based at Mayo Clinic campuses in Minnesota and Florida. It's one of more than 30 Alzheimer's disease research centers in the United States designated and funded by the National Institute on Aging of the National Institutes of Health.
  • Researchers in the center study frontotemporal dementia, Alzheimer's disease and related conditions. You may have the opportunity to participate in clinical trials in the center. Mayo Clinic's campus in Arizona is part of the Arizona Alzheimer's Consortium, a statewide research collaboration.
  • Mayo Clinic researchers are currently coordinating a large National Institutes of Health-funded study called ALLFTD that follows individuals with sporadic and familial frontotemporal dementia and associated conditions.

Read more about research in:

Publications

See a list of publications about frontotemporal dementia by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

  1. Frontotemporal disorders. National Institute of Neurological Disorders and Stroke. https://www.ninds.nih.gov/disorders/all-disorders/frontotemporal-dementia-information-page. Accessed Aug. 30, 2023.
  2. Loscalzo J, et al., eds. Frontotemporal dementia. In: Harrison's Principles of Internal Medicine. 21st ed. McGraw Hill; 2022. https://accessmedicine.mhmedical.com. Accessed Aug. 30, 2023.
  3. Ulugut H, et al. Frontotemporal dementia: Past, present and future. Alzheimer's & Dementia. 2023; doi:10.1002/alz.13363.
  4. Grossman M, et al. Frontotemporal lobar degeneration. Nature Reviews: Disease Primers. 2023; doi:10.1038/s41572-023-00447-0.
  5. Antonioni A, et al. Frontotemporal dementia, where do we stand? A narrative review. International Journal of Molecular Sciences. 2023; doi:10.3390/ijms241411732.
  6. Diagnosing FTD. The Association for Frontotemporal Degeneration. https://www.theaftd.org/for-health-professionals/diagnosing-ftd/. Accessed Aug. 30, 2023.
  7. What are frontotemporal disorders? Causes, symptoms and treatment. National Institute on Aging. https://www.nia.nih.gov/health/what-causes-frontotemporal-disorders. Accessed Aug. 30, 2023.
  8. Lee SE, et al. Frontotemporal dementia: Treatment. https://www.uptodate.com/contents/search. Accessed Aug. 30, 2023.
  9. Ferri FF. Frontotemporal dementia. In: Ferri's Clinical Advisor 2024. Elsevier; 2024. https://www.clinicalkey.com. Accessed Aug. 30, 2023.
  10. The ALLFTD team. ARTFL LEFTDS Longitudinal Frontotemporal Lobar Degeneration. https://www.allftd.org/allftd-executive-team. Accessed Sept. 6, 2023.
  11. Providing care for a person with a frontotemporal disorder. National Institute on Aging. https://www.nia.nih.gov/health/providing-care-person-frontotemporal-disorder. Accessed Aug. 30, 2023.
  12. Ami TR. Allscripts EPSi. Mayo Clinic. Sept. 4, 2023.
  13. Alzheimer's disease research centers. National Institute on Aging. https://www.nia.nih.gov/health/alzheimers-disease-research-centers. Accessed Aug. 30, 2023.
  14. Participating institutions. Arizona Alzheimer's Consortium. http://azalz.org/about-us/participating-institutions/. Accessed Aug. 30, 2023.