Fibromyalgia symptoms often mimic those of other conditions. Determining the true cause of your symptoms is key to receiving proper treatment.

By Mayo Clinic Staff

Fibromyalgia symptoms include widespread body pain, fatigue, unrefreshing sleep and mood problems. But all of these symptoms are common to many other conditions. And because fibromyalgia symptoms can occur alone or along with other conditions, it can take time to tease out which symptom is caused by what problem.

To make things even more confusing, fibromyalgia symptoms can come and go over time. That's why it can take a long time to go from fibromyalgia symptoms to a fibromyalgia diagnosis.

Fibromyalgia appears to be linked to changes in how the brain and spinal cord process pain signals. As a result, your doctor will usually rely on your group of symptoms to make a diagnosis.

Diagnostic guidelines from the American College of Rheumatology now include widespread pain throughout your body for at least three months. "Widespread" is defined as pain on both sides of your body, as well as above and below your waist.

Fibromyalgia is also often characterized by additional pain when firm pressure is applied to specific areas of your body, called tender points. In the past, at least 11 of these 18 spots had to test positive for tenderness to diagnose fibromyalgia.

However, given that fibromyalgia symptoms can come and go, a person might have 11 tender points one day but only eight tender points on another day. And many doctors were uncertain about how much pressure to apply during a tender point exam.

While specialists or researchers may still use tender points, they are no longer required for your family doctor to make a diagnosis of fibromyalgia.

It's important to determine whether your symptoms are caused by some other underlying problem. Common culprits include:

  • Rheumatic diseases. Certain conditions — such as rheumatoid arthritis, Sjogren's syndrome and lupus — can begin with generalized aches and pain.
  • Mental health problems. Disorders such as depression and anxiety often feature generalized aches and pain.
  • Neurological disorders. In some people, fibromyalgia causes numbness and tingling, symptoms that mimic those of disorders such as multiple sclerosis and myasthenia gravis.

Your doctor may want to rule out other conditions that may have similar symptoms. Blood tests may include:

  • Complete blood count
  • Erythrocyte sedimentation rate
  • Cyclic citrullinated peptide test
  • Rheumatoid factor
  • Thyroid function tests
  • Anti-nuclear antibody
  • Celiac serology
  • Vitamin D

Your doctor may also perform a careful physical exam of your muscles and joints, as well as a neurological exam to look for other causes of your symptoms. If there's a chance that you may be suffering from sleep apnea, your doctor may recommend a sleep study.

People who have fibromyalgia also often wake up tired, even after they've slept continuously for more than eight hours. Brief periods of physical or mental exertion may leave them exhausted. They may also have problems with short-term memory and the ability to concentrate. If you have these problems, your doctor may ask you to rank how severely they affect your day-to-day activities.

Fibromyalgia often coexists with other health problems, so your doctor may also ask if you experience:

  • Irritable bowel syndrome
  • Headaches
  • Jaw pain
  • Anxiety or depression
  • Frequent or painful urination

In some cases, fibromyalgia symptoms begin shortly after a person has experienced a mentally or physically traumatic event, such as a car accident. People who have post-traumatic stress disorder appear to be more likely to develop fibromyalgia, so your doctor may ask if you've experienced any traumatic events recently.

Because genetic factors appear to be involved in fibromyalgia, your doctor may also want to know if any other members of your immediate family have experienced similar symptoms.

All of this information taken together will give your doctor a much better idea of what may be causing your symptoms. And that's crucial to developing an effective treatment plan.

Sept. 18, 2020