Corticobasal degeneration

By Mayo Clinic Staff
Aug. 11, 2026

Research

Mayo Clinic staff actively conducts research in corticobasal degeneration and related conditions. Researchers study causes, diagnostic techniques and treatment options for corticobasal degeneration.

The Alzheimer's Disease Research Center at Mayo Clinic in Minnesota and Mayo Clinic in Florida are two of more than 30 Alzheimer's disease research centers in the United States designated and funded by the National Institute on Aging of the National Institutes of Health.

Researchers in the center study corticobasal degeneration, dementia, Alzheimer's disease and related conditions. You may have the opportunity to participate in trials at the center. Mayo Clinic is a key participant in the Arizona Alzheimer's Consortium, a statewide research collaboration.

Publications

See a list of publications about corticobasal degeneration by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

  1. Factor SA, et al. Corticobasal degeneration. https://www.uptodate.com/contents/search. Accessed Nov. 6, 2025.
  2. Ropper AH, et al. Degenerative diseases of the nervous system. In: Adams and Victor's Principles of Neurology. 12th ed. McGraw Hill; 2023. https://accessmedicine.mhmedical.com. Accessed Nov. 6, 2025.
  3. Corticobasal degeneration. National Institute of Neurological Disorders and Stroke. https://www.ninds.nih.gov/Disorders/All-Disorders/Corticobasal-Degeneration-Information-Page. Accessed Nov. 6, 2025.
  4. Jankovic J, et al., eds. Alzheimer's disease and other dementias. In: Bradley and Daroff's Neurology in Clinical Practice. 8th ed. Elsevier; 2022. https://www.clinicalkey.com. Accessed Nov. 6, 2025.
  5. Budson AE, et al. Corticobasal degeneration and corticobasal syndrome. In: Memory Loss, Alzheimer's Disease, and Dementia. 3rd ed. Elsevier; 2022. https://www.clinicalkey.com. Accessed Nov. 6, 2025.
  6. Koga S, et al. Neuropathology and emerging biomarkers in corticobasal syndrome. Journal of Neurology, Neurosurgery and Psychiatry. 2022; doi:10.1136/jnnp-2021-328586.
  7. Alzheimer's disease research centers. National Institute on Aging. https://www.nia.nih.gov/health/alzheimers-disease-research-centers. Accessed Nov. 6, 2025.
  8. Jellinger KA. The spectrum of cognitive impairment in atypical parkinsonism syndromes: A comprehensive review of current understanding and research. Diseases. 2025; doi:10.3390/diseases13020039.
  9. Mena AM, et al. Imaging pathological tau in atypical parkinsonisms: A review. Clinical Parkinsonism and Related Disorders. 2022; doi:10.1016/j.prdoa.2022.100155.
  10. Ami TR. Allscripts EPSi. Mayo Clinic. Sept. 4, 2023.
  11. Aiba I, et al. Clinical course of pathologically confirmed corticobasal degeneration and corticobasal syndrome. Brain Communications. 2023; doi:10.1093/braincomms/fcad321.
  12. Shir D, et al. Clinicoradiologic and neuropathologic evaluation of corticobasal syndrome. Neurology. 2023; doi:10.1212/WNL.0000000000207397.
  13. Medical review (expert opinion). Mayo Clinic. Nov. 5, 2025.
  14. Nouh CD, et al. Diagnosis and management of progressive corticobasal syndrome. Current Treatment Options in Neurology. 2024; doi:10.1007/s11940-024-00797.
  15. Singh NA, et al. Relationships between PET and blood plasma biomarkers in corticobasal syndrome. Alzheimer's & Dementia: The Journal of the Alzheimer's Association. 2024; doi:10.1002/alz.13914.